ABOUT THE MECHANISM OF ALLERGIC PHENOMENA IN THE APPLICATION OF MEDICINAL SUBSTANCES
- Authors: Rakhmatullin I.M.1, Tolpegina T.B.1
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Affiliations:
- Department of Pathological Physiology (Head - Doctor of Medical Sciences M.A.Yerzin) Kazan Medical Institute
- Issue: Vol 40, No 5 (1959)
- Pages: 89-94
- Section: Articles
- URL: https://journal-vniispk.ru/kazanmedj/article/view/62104
- DOI: https://doi.org/10.17816/kazmj62104
- ID: 62104
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Abstract
For a long time, cases of complications with the use of various medicinal substances have been described in the medical literature. Complications were noted with the action of iodine drugs, pyramidone, quinine, salvarsan, barbiturates, hormones, etc. In recent years, sulfa drugs and antibiotics have found widespread use among drugs. Suffice it to say that, according to the literature, more than half of all recent prescriptions in the United States were antibiotic prescriptions. At the same time, if at the dawn of the use of these drugs complications were quite rare, then as clinical observations accumulated, the facts of certain side effects began to emerge - from skin rashes to severe general reactions resembling anaphylactic shock. Such reactions do not make up a large percentage of all cases of using these drugs, but the fact that they can sometimes be severe and worsen the course of the underlying disease attracts the attention of doctors.
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##article.viewOnOriginalSite##About the authors
I. M. Rakhmatullin
Department of Pathological Physiology (Head - Doctor of Medical Sciences M.A.Yerzin) Kazan Medical Institute
Author for correspondence.
Email: info@eco-vector.com
Russian Federation
T. B. Tolpegina
Department of Pathological Physiology (Head - Doctor of Medical Sciences M.A.Yerzin) Kazan Medical Institute
Email: info@eco-vector.com
Russian Federation
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