Indications for the use of the tranquilizer mebikar
- Authors: Avdonina N.A.1, Braunagel A.L.1, Zaikonnikova I.V.1, Zimakova I.E.1, Zimakov U.A.1, Chudnovskiy V.S.1, Karpov A.M.1
-
Affiliations:
- Medical Institute named after S. V. Kuratova, Kazan city neuropsychiatric dispensary. V. M. Bekhtereva
- Issue: Vol 55, No 5 (1974)
- Pages: 65-66
- Section: Articles
- URL: https://journal-vniispk.ru/kazanmedj/article/view/63194
- DOI: https://doi.org/10.17816/kazmj63194
- ID: 63194
Cite item
Full Text
Abstract
Mebikar, one of the derivatives of bicyclic ureas (2,4,6,8-tetramegyl-2, 4, 6, 8-tetraazobicyclo [3, 3, 0] -octanedione-3, 7), was synthesized by L. V. Epishina and OV Lebedev at the Institute of Organic Chemistry. ND Zelinsky Academy of Sciences of the USSR. The study of the biological activity of this series of compounds showed that mebikar has a deprimating effect on the central nervous system of animals. The drug has a protective effect against group toxicity of phenamine and at a dose of 1/15 DMT (200 mg / kg) significantly inhibits research reactions in white mice.
Keywords
Full Text
##article.viewOnOriginalSite##About the authors
N. A. Avdonina
Medical Institute named after S. V. Kuratova, Kazan city neuropsychiatric dispensary. V. M. Bekhtereva
Author for correspondence.
Email: info@eco-vector.com
Department of Pharmacology, Department Psychiatry
Russian FederationA. L. Braunagel
Medical Institute named after S. V. Kuratova, Kazan city neuropsychiatric dispensary. V. M. Bekhtereva
Email: info@eco-vector.com
Department of Pharmacology, Department Psychiatry
Russian FederationI. V. Zaikonnikova
Medical Institute named after S. V. Kuratova, Kazan city neuropsychiatric dispensary. V. M. Bekhtereva
Email: info@eco-vector.com
Department of Pharmacology, Department Psychiatry
Russian FederationI. E. Zimakova
Medical Institute named after S. V. Kuratova, Kazan city neuropsychiatric dispensary. V. M. Bekhtereva
Email: info@eco-vector.com
Department of Pharmacology, Department Psychiatry
Russian FederationU. A. Zimakov
Medical Institute named after S. V. Kuratova, Kazan city neuropsychiatric dispensary. V. M. Bekhtereva
Email: info@eco-vector.com
Department of Pharmacology, Department Psychiatry
Russian FederationV. S. Chudnovskiy
Medical Institute named after S. V. Kuratova, Kazan city neuropsychiatric dispensary. V. M. Bekhtereva
Email: info@eco-vector.com
Department of Pharmacology, Department Psychiatry
Russian FederationA. M. Karpov
Medical Institute named after S. V. Kuratova, Kazan city neuropsychiatric dispensary. V. M. Bekhtereva
Email: info@eco-vector.com
Department of Pharmacology, Department Psychiatry
Russian FederationReferences
Supplementary files
