Features of immunity in patients with diphtheria
- Authors: Lebenzon S.S.1,2, Mayansky D.N.1,2, Spiridonova E.A.1,2, Vasyunin A.V.1,2, Altukhova I.V.1,2, Garbuzova S.B.1,2
 - 
							Affiliations: 
							
- Novosibirsk Medical Institute
 - Institute of Clinical and Experimental Medicine, Siberian Branch of the USSR Academy of Medical Sciences
 
 - Issue: Vol 63, No 5 (1982)
 - Pages: 41-42
 - Section: Articles
 - URL: https://journal-vniispk.ru/kazanmedj/article/view/64519
 - DOI: https://doi.org/10.17816/kazmj64519
 - ID: 64519
 
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Abstract
The indices of humoral and cellular immunity were studied in 10 patients with typical and 7 atypical (carriage) forms of diphtheria infection. The highest level of antibodies (4.25 ± 1.2 AU / ml) was in carriers of diphtheria bacteria, and the lowest (0.07 AU / ml) was in patients with toxic diphtheria. Disturbances in the structure of cellular immunogomeostasis - a decrease in the total number of T-lymphocytes, an increase in Ta-ROK, an increase in the functional activity of phagocytic neutrophils and peripheral blood monocytes - were found in all and were most pronounced in patients with toxic diphtheria. In children, according to epidemiological indications, vaccinated with ADS, while the number of T-lymphocytes was preserved, all other studied parameters turned out to be increased.
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##article.viewOnOriginalSite##About the authors
S. S. Lebenzon
Novosibirsk Medical Institute; Institute of Clinical and Experimental Medicine, Siberian Branch of the USSR Academy of Medical Sciences
							Author for correspondence.
							Email: info@eco-vector.com
				                					                																			                												                	Russian Federation													
D. N. Mayansky
Novosibirsk Medical Institute; Institute of Clinical and Experimental Medicine, Siberian Branch of the USSR Academy of Medical Sciences
														Email: info@eco-vector.com
				                					                																			                												                	Russian Federation													
E. A. Spiridonova
Novosibirsk Medical Institute; Institute of Clinical and Experimental Medicine, Siberian Branch of the USSR Academy of Medical Sciences
														Email: info@eco-vector.com
				                					                																			                												                	Russian Federation													
A. V. Vasyunin
Novosibirsk Medical Institute; Institute of Clinical and Experimental Medicine, Siberian Branch of the USSR Academy of Medical Sciences
														Email: info@eco-vector.com
				                					                																			                												                	Russian Federation													
I. V. Altukhova
Novosibirsk Medical Institute; Institute of Clinical and Experimental Medicine, Siberian Branch of the USSR Academy of Medical Sciences
														Email: info@eco-vector.com
				                					                																			                												                	Russian Federation													
S. B. Garbuzova
Novosibirsk Medical Institute; Institute of Clinical and Experimental Medicine, Siberian Branch of the USSR Academy of Medical Sciences
														Email: info@eco-vector.com
				                					                																			                												                	Russian Federation													
References
- Покровский В. И., Авербах М. М„ Литвинов В. И., Рубцов И. В. Приобретенный иммунитет и инфекционный процесс. М., Медицина, 1979.
 
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