Changes in the sensitivity of pyogenic staphylococci to certain antibiotics

Abstract

The problem of resistance of pathogenic microbes, including pyogenic staphylococci, to antibiotics is one of the most pressing problems of medicine. A large number of studies have been devoted to this issue in recent years (5, 6, 7, 9, 10, 14, 15, 16, 17, 18, 19, 22, 23), from which it is clearly seen that the wide and not always correct use of the indicated drugs in the treatment of patients led to the massive appearance of resistant forms of microbes and a decrease in the effectiveness of antibiotic therapy. G. Ya. Kivman (10) in a review of foreign literature on this issue indicates that in the first years of the use of penicillin (1924-1944) mortality from staphylococcal septicemia decreased from 80 to 23%. Recently, it has again increased to 50, and according to Reiman's data, to 53%.

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