Features of the clinical course of peptic ulcer disease in combination with reflux esophagitis

With a comprehensive examination, including endoscopy, reflux esophagitis in patients with peptic ulcer disease is detected much more often than without: the use of endoscopy. In patients with duodenal ulcer, it was found in 30.6%, in patients with gastric ulcer - in 17.6%, after gastric resection in 21.6%. The conditions contributing to the development of reflux esophagitis are hernia of the esophageal opening of the diaphragm, aerophagia, work associated with frequent sharp bends and bending of the trunk, with a prolonged forced working posture, which causes an increase in intra-abdominal pressure. With reflux esophagitis, it is necessary to make adjustments to the course of antiulcer treatment: care should be taken in prescribing anticholinergics, giving preference to drugs such as metoclopramides, insoluble alkalis with anesthetics.