Thrombosis risks of permanent vascular access
- Authors: Staroverov I.N.1,2, Noshchenko N.S.1,2, Shubin L.B.1
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Affiliations:
- Yaroslavl State Medical University
- Regional Clinical Hospital
- Issue: Vol 27, No 2 (2019)
- Pages: 203-208
- Section: Original study
- URL: https://journal-vniispk.ru/pavlovj/article/view/14540
- DOI: https://doi.org/10.23888/PAVLOVJ2019272203-208
- ID: 14540
Cite item
Abstract
Aim. To identify the factors affecting the occurrence of thrombosis of permanent vascular access and to determine their significance.
Materials and Methods. The results of treatment of 168 patients with native arteriovenous radio-cephalic fistula were analyzed. The results of treatment were traced within 1 year. According to the results of treatment, patients were divided into 2 groups: the 1st group – patients who did not develop thrombosis of the arteriovenous fistula within 1 year of hemodialysis, and the 2nd group – patients with a dysfunction of permanent vascular access developed due to thrombosis within the first year.
Results. On the basis of the obtained data, the risk factors for thrombosis of permanent vascular access within 6 months were: repeated operations, duration of anticoagulant therapy, correction of anticoagulant therapy, antibiotic therapy. Risk factors for thrombosis of the PVA for the period from 6 months to 12 months were: atherosclerosis, fistula vein diameter, repeated operations, the number of repeated operations, a reason for a repeated operation, duration of anticoagulant therapy, correction of anticoagulant therapy, antibiotic therapy.
Conclusions. The results of the study suggest that the realization of the identified risk factors is not the only cause of complications. For a more detailed consideration of the probability for thrombosis of permanent vascular access in different time intervals, it seems appropriate to use multidimensional mathematical modeling.
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##article.viewOnOriginalSite##About the authors
Ilya N. Staroverov
Yaroslavl State Medical University; Regional Clinical Hospital
Email: vestnik@rzgmu.ru
ORCID iD: 0000-0001-9855-9467
SPIN-code: 8011-7176
ResearcherId: М-8174-2014
MD, PhD, Associate Professor, , Head of the Surgery Department of Postgraduate Education Institute, Head of the Department of Vascular Surgery
Russian Federation, Yaroslavl; YaroslavlNikita S. Noshchenko
Yaroslavl State Medical University; Regional Clinical Hospital
Author for correspondence.
Email: noschenko.ns@gmail.com
ORCID iD: 0000-0001-7770-4370
SPIN-code: 4755-6307
ResearcherId: A-7229-2019
PhD-Student of the Surgery Department of Postgraduate Education Institute, Cardiovascular surgeon of the Department of Vascular Surgery
Russian Federation, Yaroslavl; YaroslavlLeonid B. Shubin
Yaroslavl State Medical University
Email: vestnik@rzgmu.ru
ORCID iD: 0000-0003-4562-7731
SPIN-code: 8021-7289
ResearcherId: A-9339-2019
MD, PhD, Associate Professor of the Department of Pathological Anatomy
Russian Federation, YaroslavlReferences
- Bashar K, Adeel Z, Elsheikh S, et al. Predictive Parameters of Arteriovenous Fistula Functional Maturation in a Population of Patients with End-stage Renal Disease. European Journal of Vascular and Endovascular Surgery. 2016;52(6):76. doi:10. 4103/0971-4065.134656
- Soheilipour M, Shahidi S. Comparison of vascular access use in hemodialysis patients in Isfahan in 2003 and 2013. Indian Journal of Nephrology. 2015;25(1):16. doi: 10.4103/0971-4065.134656
- Smith G, Barnes R, Fagan M, et al. The Impact of Vein Mechanical Compliance on Arteriovenous Fistula Outcomes. Annals of Vascular Surgery. 2016;(32):9-14. doi: 10.1016/j.avsg.2015.11.002
- Yeh C, Huang T, Wang Y, et al. Effects of Antiplatelet Medication on Arteriovenous Fistula Patency After Surgical Thrombectomy. Current Vascular Pharmacology. 2016;14(4):353-9. doi:10.2174/ 1570161114666160229115844
- Tanner N, Da Silva A. Medical adjuvant treatment to increase patency of arteriovenous fistulae and grafts. Cochrane Database of Systematic Reviews. 2015;16(7):34. doi: 10.1002/14651858.CD002786.pub3
- King D, Paulson W, Al-Qaisi M, et al. Volume Blood Flow, Static Pressure Ratio and Venous Conductance in Native Arterio-venous Fistulae: Three Surveillance Methods Compared. The Journal of Vascular Access. 2015;16(3):211-7. doi:10. 5301/jva.5000324
- Morton S, Rodríguez A, Morris D, et al. A Systematic Review and Meta-Analysis of Circulating Biomarkers Associated with Failure of Arteriovenous Fistulae for Haemodialysis. PLOS ONE. 2016; 11(7):e0159963. doi: 10.1371/journal.pone.0159963
- Rebrova OYu. Statisticheskij analiz meditsinskikh dannykh. Primenenie paketa prikladnykh programm STATISTICA. Moscow: Mediasfera; 2002. (In Russ).
- Fletcher RH, Fletcher SW, Wagner EH. Clinical Epidemiology: The Essentials. Williams & Wilkins; 1996.
- Fekih-Mrissa N, Sayeh A, Baffoun A, et al. Association Between Thrombophilic Gene Mutations and the Risk of Vascular Access Thrombosis in Hemodialysis Patients. Therapuetic Apheresis and Dialysis. 2016;20(2):107-11. doi: 10.1111/1744-9987.12379
- Kalinin RE, Egorov AA, Suchkov IA, et al. Effect of genetic polymorphisms on functioning of a permanent vascular access in patients on dialysis. Angiology and Vascular Surgery. 2019;25(1):40-4. (In Russ). doi: 10.33529/angio2019105
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