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Post a Comment VEB-mononucleosis in children at the hospital stage in modern conditions
- Authors: Timchenko V.N.1, Bannova S.L.1, Pavlova N.V.1, Pavlova E.B.1, Kaplina T.A.1, Fedorova A.V.1, Bulina O.V.1, Balashov A.L.1, Hakizimana J.1
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Affiliations:
- St. Petersburg State Pediatric Medical University
- Issue: Vol 9, No 6 (2018)
- Pages: 77-82
- Section: Articles
- URL: https://journal-vniispk.ru/pediatr/article/view/11228
- DOI: https://doi.org/10.17816/PED9677-82
- ID: 11228
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Abstract
VEB-mononucleosis is an actual infection of childhood. We analyzed 764 medical records of inpatients with VEB mononucleosis. Two groups of patients were formed: group I (young age) was 411 people (from 1 to 7 years), group II (school age) 353 people (from 7 to 17 years). In the I group, boys predominated, the peak of the disease occurred in the spring period, in group II – girls, the incidence of the incidence was noted in the winter. In both groups, moderate forms of the disease predominated, 684 people (89.5%). Severe forms of the disease prevailed in the children of group II. In group I the disease began acutely, and in the second group – subacute. In both groups, the whole syndrome of VEB mononucleosis was observed: fever, intoxication, acute tonsillitis, lymphadenopathy. The defeat of the nasopharynx and hepatosplenomegaly was more common in the I group. In this case, the increase in the size of the liver and spleen was up to 2 cm from the age norm. In the biochemical analysis of blood, an increase in ALT activity was detected with the same frequency in both age groups. Moreover, in the I group there was a moderate activity of ALT, in the II group – more significant. In clinical blood analysis, most patients in both age groups had leukocytosis. Lymphocytosis was more common in children of group I. Monocytosis was more common in children of group II. Increased ESR was observed in both groups with the same frequency. Atypical mononucleary in children of the I group appeared on the first, and in the older group – on the second week of the disease. A set of laboratory methods was used to diagnose VEB mononucleosis. In 100% of the observed children receiving viferon, there was a significant decrease in the duration of fever, intoxication, acute tonsillitis, lymphadenopathy, adenoiditis, hepatomegaly, splenomegaly and reduction in hospital stay.
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##article.viewOnOriginalSite##About the authors
Vladimir N. Timchenko
St. Petersburg State Pediatric Medical University
Author for correspondence.
Email: detinfection@mail.ru
MD, PhD, Dr Med Sci, Professor, Head, Department of Infectious Diseases in Children named after Prof. M.G. Danilevich
Russian Federation, Saint PetersburgSvetlana L. Bannova
St. Petersburg State Pediatric Medical University
Email: detinfection@mail.ru
MD, PhD Associate Professor, Department of Infectious Diseases in Children named after Prof. M.G. Danilevich
Russian Federation, Saint PetersburgNatalia V. Pavlova
St. Petersburg State Pediatric Medical University
Email: detinfection@mail.ru
MD, PhD Assistant Professor, Department of Infectious Diseases in Children named after Prof. M.G. Danilevich
Russian Federation, Saint PetersburgElena B. Pavlova
St. Petersburg State Pediatric Medical University
Email: detinfection@mail.ru
MD, PhD Associate Professor, Department of Pharmacology
Russian Federation, Saint PetersburgTatyana A. Kaplina
St. Petersburg State Pediatric Medical University
Email: detinfection@mail.ru
MD, PhD Associate Professor, Department of Infectious Diseases in Children named after Prof. M.G. Danilevich
Russian Federation, Saint PetersburgAnna V. Fedorova
St. Petersburg State Pediatric Medical University
Email: detinfection@mail.ru
Assistant Professor, Department of Infectious Diseases in Children named after Prof. M.G. Danilevich
Russian Federation, Saint PetersburgOksana V. Bulina
St. Petersburg State Pediatric Medical University
Email: detinfection@mail.ru
MD, PhD Associate Professor, Department of Rehabilitation AF and DPO
Russian Federation, Saint PetersburgAlexey L. Balashov
St. Petersburg State Pediatric Medical University
Email: balashovAL7@yandex.ru
Associate Professor, Department of Propedeutics of Children's Diseases with a Course of General Care
Russian Federation, Saint PetersburgJean-Claude Hakizimana
St. Petersburg State Pediatric Medical University
Email: detinfection@mail.ru
Postgraduate Student, Department of Infectious Diseases in Children named after Prof. M.G. Danilevich
Russian Federation, Saint PetersburgReferences
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