The nature of relationship between some health parameters in infants born with hypoplastic type mild intrauterine growth retardation
- Authors: Ivanov D.O.1, Derevtsov V.V.2
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Affiliations:
- St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
- St. Lukaʼs Clinical Research Center for Children
- Issue: Vol 11, No 2 (2020)
- Pages: 15-24
- Section: Original studies
- URL: https://journal-vniispk.ru/pediatr/article/view/120340
- DOI: https://doi.org/10.17816/PED11215-24
- ID: 120340
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Abstract
Objective. Assessing the relationship between health indicators in infants born with intrauterine growth retardation (JGR) of hypoplastic type of mild severity among themselves, compared with infants born without IGR, and with practically healthy infants from practically healthy mothers.
Materials and methods. Under the supervision were 109 infants. From mothers with a burdened somatic and obstetric-gynecological history, 84 children were born: 15 (gr. 1) – with mild of hypo-plastic type IGR, 69 (gr. 2) – without IGR. The control group (gr. 3) consisted of 25 healthy children born to healthy mothers. All observed babies were born full-term. They were examined in dynamics at the age of 1 (n = 104), 3 (n = 98), 6 (n = 92), 12 (n = 94) months. Outcome recording methods were a comprehensive case history analysis, physical examination, assessment of electrocar-diography and cardiointervalography. Distribution-free statistical analysis methods.
Results. A correlation was found at 2–3 days between weight and body length (r = 0.63), body weight and stress index (r = –0.56), sympathetic activity and stress index (r = 0.84), intraatrial and atrioventricular conductivity (r = 0.64); at 1 month between sympathetic activity and stress index (r = 0.62); at 3 months between weight and body length (r = 0.79), sympathetic activity and stress index (r = 0.87), sympathetic activity and intraventricular conduction (r = 0.67), intraatrial and atrioventricular conduction (r = 0.71); at 6 months between weight and body length (r = 0.81), body weight and intraatrial conduction (r = 0.65), body weight and electric systole (r = –0.58), sympathetic activity and stress index (r = 0.92); at 12 months between body length and intraatrial (r = 0.74), body length and atrioventricular conduction (r = 0.76), sympathetic activity and stress index (r = 0.94), sympathetic activity and electrical systole (r = –0.71), stress index and intraventricular conduction (r = 0.68), stress index and electric systole (r = –0.69), intraatrial and stress index (r = 0.9), atrioventricular conduction and electric systole (r = 0.63).
Conclusions. The revealed correlation communications between of some studied parameters allow doctors to allocate groups of dispensary observation, to diagnose changes at early stages of the pathological process, conduct correctional actions with assessment of their efficiency.
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##article.viewOnOriginalSite##About the authors
Dmitry O. Ivanov
St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Author for correspondence.
Email: doivanov@yandex.ru
MD, PhD, Dr Med Sci, Professor, Rector
Russian Federation, Saint PetersburgVitaly V. Derevtsov
St. Lukaʼs Clinical Research Center for Children
Email: VitalyDerevtsov@gmail.com
MD, PhD, Head of Clinical and Diagnostic Department
Russian Federation, MoscowReferences
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