Acute methadone poisoning in infants
- Authors: Udaltcov M.A.1, Pshenisnov K.V.2, Aleksandrovich Y.S.2, Kaziakhmedov V.A.2, Pochinyaeva L.M.1, Storozhuk O.D.2
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Affiliations:
- N.F. Filatov St. Petersburg State Health Care Institution Child City Clinical Hospital No. 5
- Saint Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
- Issue: Vol 11, No 2 (2020)
- Pages: 93-99
- Section: Clinical observation
- URL: https://journal-vniispk.ru/pediatr/article/view/120349
- DOI: https://doi.org/10.17816/PED11293-99
- ID: 120349
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Abstract
Acute poisoning in children is one of the most frequent reasons for seeking medical care and hospitalization in intensive care units, but it is extremely rare in children of the first year of life. On the example of the clinical case, the peculiarities of the course of acute severe methadone poisoning in a two-month-old child against the background of natural feeding are considered. The main data of history and clinical-laboratory examination are reflected, which allowed to suspect acute poisoning in a timely manner and to carry out reasonable intensive therapy, against the background of which the maximum rapid improvement of the child ‘s condition is achieved. The algorithm of differential diagnosis of comatose state in children is presented, which can be used in all cases of sudden suppression of consciousness of unclear genesis. Special attention is paid to the need for maximum early recognition of exogenous poisoning and targeted pathogenetic treatment aimed at elimination of toxicant metabolites. A distinctive feature of this case was the severe course of acute methadone poisoning in the infant with the development of coma and respiratory distress, which regressed against the background of the treatment carried out with the full recovery of the patient.
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##article.viewOnOriginalSite##About the authors
Maksim A. Udaltcov
N.F. Filatov St. Petersburg State Health Care Institution Child City Clinical Hospital No. 5
Author for correspondence.
Email: udalmax@yandex.ru
Anesthesiologist and Intensivist, Department of Anesthesiology and Intensive Care
Russian Federation, Saint PetersburgKonstantin V. Pshenisnov
Saint Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: Psh_k@mail.ru
MD, PhD, Associate Professor, Department of Anesthesiology, Intensive Care and Emergency Pediatrics Postgraduate Education
Russian Federation, Saint PetersburgYuriy S. Aleksandrovich
Saint Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: Jalex1963@mail.ru
MD, PhD, Dr Med Sci, Professor, Head, Department of Anesthesiology, Intensive Care and Emergency Pediatrics Postgraduate Education
Russian Federation, Saint PetersburgVitaliy A. Kaziakhmedov
Saint Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: vac-spb@yandex.ru
MD, PhD, Associate Professor, Department of Anesthesiology, Intensive Care and Emergency Pediatrics Postgraduate Education
Russian Federation, Saint PetersburgLyubov M. Pochinyaeva
N.F. Filatov St. Petersburg State Health Care Institution Child City Clinical Hospital No. 5
Email: pochvalub@mail.ru
Chief Physician for Treatment
Russian Federation, Saint PetersburgOlga D. Storozhuk
Saint Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: storoshuk@rambler.ru
Anesthesiologist and Intensivist, Department of Anesthesiology and Intensive Care
Russian Federation, Saint PetersburgReferences
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