Autonomic and endothelial dysfunction with neurocirculatory asthenia in young men of call-up age
- Authors: Ivanov V.S.1, Levina L.I.1, Ivanov S.N.1, Vasilenko V.S.1
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Affiliations:
- St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
- Issue: Vol 10, No 2 (2019)
- Pages: 27-31
- Section: Articles
- URL: https://journal-vniispk.ru/pediatr/article/view/13509
- DOI: https://doi.org/10.17816/PED10227-31
- ID: 13509
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Abstract
Young men of call-up age with neurocirculatory were asthenia were examined for autonomic regulation of cardiac activity and vasodilatory reserve of the arteries. The functional state of the autonomic nervous system (ANS) was studied with the aid of rythmography with analyse of heart rate variability. The following parameters were studied: vegetative regulation type, responsiveness of departments of ANS and autonomic provision of cardiac activity. The type of vegetative regulation was determined by the mean value of RR interval and indication of the heart rate variability (∆RR). Reactivity of parasympathetic and sympathetic divisions of the ANS and autonomic support of cardiac activity were investigated using breathing test. To ensure vegetative dysadaptation cardiac activity includes reaction with low vegetative coverage of both divisions of the ANS and paradoxical reaction in which there is a decrease in ∆RRmax (instead of increase) and an increase in ∆RRmin instead of decrease. These reactions indicate autonomic dysfunction. Vasodilatory reserve of the arteries was investigated using ultrasonography of the brachial artery with compressive sample and determination of endothelium-dependent vasodilation. It was found that in boys with neurocirculatory asthenia vagotonic and sympathetic types of vegetative regulation are often determined by disadaptative vegetative provision of cardiac activity, which is accompanied by endothelial dysfunction with reduced vasodilator reserve of the arteries.
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##article.viewOnOriginalSite##About the authors
Vladimir S. Ivanov
St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Author for correspondence.
Email: v.sivanov@yandex.ru
MD, PhD, Associate Professor of Department of Hospital Therapy with Endocrinology Course
Russian Federation, Saint PetersburgLilia I. Levina
St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: tani_tani@mail.ru
MD, PhD, Dr Med Sci, Professor of Department of Hospital Therapy with Endocrinology Course
Russian Federation, Saint PetersburgSergey N. Ivanov
St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: s.nivanov@yandex.ru
MD, PhD, Associate Professor of Department of Hospital Therapy with Endocrinology Course
Russian Federation, Saint PetersburgVladimir S. Vasilenko
St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
Email: vasilenkovladi@yandex.ru
MD, PhD, Dr Med Sci, Professor, Head of Department of Hospital Therapy with Endocrinology Course
Russian Federation, Saint PetersburgReferences
- Земцовский Э.В., Матус К.М., Санкин А.Н. Современные технологии при исследовании сердечно-сосудистой системы. – СПб., 1997. [Zemtsovskiy EV, Matus KM, Sankin AN. Sovremennye tekhnologii pri issledovanii serdechno-sosudistoy sistemy. Saint Petersburg; 1997. (In Russ.)]
- Левина Л.И., Щеглова Л.В. Диагностика вегетативной дисфункции с помощью корреляционной ритмографии // Избранные вопросы внутренней патологии подростков / Под ред. Л.И. Левиной. – СПб.: ППМИ, 1993. – С. 23–27. [Levina LI, Shcheglova LV. Diagnostika vegetativnoy disfunktsii s pomoshch’yu korrelyatsionnoy ritmografii. In: Izbrannye voprosy vnutrenney patologii podrostkov. Ed. by L.I. Levina. Saint Petersburg: PPMI; 1993. P. 23-27. (In Russ.)]
- Лупинская З.А., Зарифьян А.Г., Гурович Т.Ц., Шлейфер С.Г. Эндотелий. Функция и дисфункция. – Бишкек: КРСУ, 2008. [Lupinskaya ZA, Zarif’yan AG, Gurovich TT, Shleyfer SG. Endoteliy. Funktsiya i disfunktsiya. Bishkek: KRSU; 2008. (In Russ.)]
- Маколкин В.И., Аббакумов С.А. Нейроциркуляторная дистония в терапевтической практике. – М.: Медицина, 1985. [Makolkin VI, Abbakumov SA. Neyrotsirkulyatornaya distoniya v terapevticheskoy praktike. Moscow: Meditsina; 1985. (In Russ.)]
- Маколкин В.И., Аббакумов С.А., Сапожникова А.А. Нейроциркуляторная дистония. – Чебоксары, 1995. [Makolkin VI, Abbakumov SA, Sapozhnikova AA. Neyrotsirkulyatornaya distoniya. Cheboksary; 1995. (In Russ.)]
- Маянская С.Д., Антонов А.Р., Попова А.А., Гребёнкина И.А. Ранние маркеры дисфункции эндотелия в динамике развития артериальной гипертонии у лиц молодого возраста // Казанский медицинский журнал. – 2009. – Т. 90. – № 1. – С. 32–37. [Mayanskaya SD, Antonov AR, Popova AA, Grebenkina IA. Early markers of endothelial dysfunction in the dynamics of the development of arterial hypertension in young people. Kazan Med Zh. 2009;90(1):32-37. (In Russ.)]
- Миронова Т.Ф., Миронов В.А., Николаенко Т.М., Барыкова Т.С. Анализ вариабельности сердечного ритма как метод неспецифической кардиодиагностики // Новые технологии в медицине: Труды научной конференции. – М., 1996. – С. 15–18. [Mironova TF, Mironov VA, Nikolaenko TM, Barykova TS. Analiz variabel’nosti serdechnogo ritma kak metod nespetsificheskoy kardiodiagnostiki. In: Novye tekhnologii v meditsine: Trudy nauchnoy konferentsii. Moscow; 1996. P. 15-18. (In Russ.)]
- Чернеховская Н.Е., Шишло В.К., Поваляев А.В. Коррекция микроциркуляции в клинической практике. – М.: Бином, 2013. [Chernekhovskaya NЕ, Shishlo VK, Povalyaev AV. Korrektsiya mikrotsirkulyatsii v klinicheskoy praktike. Moscow: Binom; 2013. (In Russ.)]
- Шишкин А.Н., Лындина М.Л. Эндотелиальная дисфункция и артериальная гипертензия // Артериальная гипертензия. – 2008. – Т. 14. – № 4. – С. 315–319. [Shishkin AN, Lyndina ML. Endothelial dysfunction and hypertension. Arterial’naia gipertenziia. 2008;14(4):315-319. (In Russ.)]
- Higashi Y, Noma K, Yoshizumi M, Kihara Y. Endothelial Function and Oxidative Stress in Cardiovascular Diseases. Circ J. 2009;73(3):411-418. https://doi.org/10.1253/circj.CJ-08-1102.
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