Features of clinical manifestations of allergic diseases in children sensitized to potatoes
- Authors: Konyukova NG1, Pampura AN2, Fedenko ES3, Khavkin AI2, Okuneva TS2, Konjukova NG4, Pampura AN4, Fedenko ES5, Havkin AI4, Okuneva TS4
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Affiliations:
- ФГУ «Московский научно-исследовательский институт педиатрии и детской хирургииМинздравсоцразвития России»
- ФГУ «Московский научно-исследовательский институт педиатрии и детской хирургии Минздравсоцразвития России»
- ФГБУ «ГНЦ Институт иммунологии» ФМБА России
- Moscow Research Institute of Pediatric and Child Surgery
- Institute of Immunology
- Issue: Vol 8, No 4 (2011)
- Pages: 55-61
- Section: Articles
- URL: https://journal-vniispk.ru/raj/article/view/121210
- DOI: https://doi.org/10.36691/RJA849
- ID: 121210
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Abstract
children with IgE-mediated sensitization to potato.
Methods. allergy tests (skin prick tests and / or the determination of specific IgE in serum by ImmunoCap, Phadia
was performed in 171 children with allergic diseases, who had sensitization to food plant proteins.
Results. sensitization to the potato found in 134 children. significant discrepancies (36%) in the results of in vitro
and in vivo tests to the potatoes were shown. sensitization to the potatoes is more common in patients with atopic
dermatitis (ad), especially in severe disease. among children with the level of specific IgE antibodies to potato
≥2 kUa / l there were more common patients with severe ad. the correlation between the level of specific IgE
antibodies to the potatoes and some of food plant proteins was found. the relationship between the concentration
of specific IgE to the potatoes and Bet v 2 was not detected.
Conclusion. the presence and concentration of specific IgE to the potatoes to a certain extent associated with
clinical manifestations of ad. the data obtained substantiate the determination of specific IgE antibodies to
potato in children with ad, especially in severe cases.
Keywords
About the authors
N G Konyukova
ФГУ «Московский научно-исследовательский институт педиатрии и детской хирургииМинздравсоцразвития России»ФГУ «Московский научно-исследовательский институт педиатрии и детской хирургииМинздравсоцразвития России»
A N Pampura
ФГУ «Московский научно-исследовательский институт педиатрии и детской хирургии Минздравсоцразвития России»
Email: apampura@pedklin.ru
ФГУ «Московский научно-исследовательский институт педиатрии и детской хирургии Минздравсоцразвития России»
E S Fedenko
ФГБУ «ГНЦ Институт иммунологии» ФМБА РоссииФГБУ «ГНЦ Институт иммунологии» ФМБА России
A I Khavkin
ФГУ «Московский научно-исследовательский институт педиатрии и детской хирургии Минздравсоцразвития России»ФГУ «Московский научно-исследовательский институт педиатрии и детской хирургии Минздравсоцразвития России»
T S Okuneva
ФГУ «Московский научно-исследовательский институт педиатрии и детской хирургии Минздравсоцразвития России»ФГУ «Московский научно-исследовательский институт педиатрии и детской хирургии Минздравсоцразвития России»
N G Konjukova
Moscow Research Institute of Pediatric and Child SurgeryMoscow Research Institute of Pediatric and Child Surgery
A N Pampura
Moscow Research Institute of Pediatric and Child SurgeryMoscow Research Institute of Pediatric and Child Surgery
E S Fedenko
Institute of ImmunologyInstitute of Immunology
A I Havkin
Moscow Research Institute of Pediatric and Child SurgeryMoscow Research Institute of Pediatric and Child Surgery
T S Okuneva
Moscow Research Institute of Pediatric and Child SurgeryMoscow Research Institute of Pediatric and Child Surgery
References
- International Union of Immunological Societies Allergen Nomenclature: IUIS official list http://www.allergen.org/search. php?allergensource=Solanum+tuberosum&searchsource=S earch.
- Ebner C., Hirschwehr R., Bauer L. et al. Identification of allergens in fruits and vegetables: IgE cross-reactivities with the important birch pollen allergens Bet v 1 and Bet v 2 (birch profilin). J. Allergy Clin. Immunol. 1995, v. 95, p. 962-969.
- Palomares O., Villalba M., Quiralte J. et al. 1,3-beta-glucanases as candidates in latex-pollen-vegetable food cross-reactivity. Clin. Exp. Allergy. 2005, v. 35 (3), p. 345-351.
- Pots A.M., Gruppen H., Hessing M. et al. Isolation and characterization of patatin isoforms. J. Agric. Food Chem. 1999, v. 47 (11), p. 4587-4592.
- Majamaa H., Seppala U., Palosuo T. et al. Positive skin and oral challenge responses to potato and occurrence of immunoglobulin E antibodies to patatin (Sol t 1) in infants with atopic dermatitis. Pediatr. Allergy Immunol. 2001, v. 12 (5), p. 283-288.
- Koppelman S.J., van Koningsveld G.A., Knulst A.C. et al. Effect of heat-induced aggregation on the IgE binding of patatin (Sol t 1) is dominated by other potato proteins. J. Agric. Food Chem. 2002, v. 50 (6), p. 1562-1568.
- Seppala U., Majamaa H., Turjanmaa K. et al. Identification of four novel potato (Solanum tuberosum) allergens belonging to the family of soybean trypsin inhibitors. Allergy. 2001, v. 56 (7), p. 619-626.
- Valueva T.A., Revina T.A., Mosolov V.V., Mentele R. Primary structure of potato kunitz-type serine proteinase inhibitor. Biol. Chem. 2000, v. 381 (12), p. 1215-1221.
- Pramod S.N., Venkatesh Y.P., Mahesh P.A. Potato lectin activates basophils and mast cells of atopic subjects by its interaction with core chitobiose of cell-bound non-specific immunoglobulin
- E. Clin. Exp. Immunol. 2007; v. 148 (3), p. 391-401. 10. De Lagrán Z.M., de Frutos F.J., de Arribas M.G., Vanaclocha- Sebastián F. Contact urticaria to raw potato. Dermatol. Online J. 2009, v. 15 (5), p.14.
- Hernández-Bel P., de la Cuadra J., García R., Alegre V. Protein Contact Dermatitis: Review of 27 Cases. Actas Dermosifiliogr. 2011, v. 102 (5), p. 336-343.
- Ikematsu K., Tachimoto H., Sugisaki C. et al. Feature of food allergy developed during infancy -relationship between infantile atopic dermatitis and food allergy. Arerugi. 2006, v. 55 (2), p. 140-150.
- Castells M.C., Pascual C., Esteban M.M., Ojeda J.A. Allergy to white potato. J. Allergy Clin. Immunol. 1986, v. 78 (6), p. 1110-1114.
- Jeannet-Peter N., Piletta-Zanin P.A., Hauser C. Facial dermatitis, contact urticaria, rhinoconjunctivitis, and asthma induced by potato. Am. J. Contact Dermat. 1999, v. 10 (1), p. 40-42.
- Beausoleil J.L., Spergel J.M., Pawlowski N.A. Anaphylaxis to raw potato. Ann. Allergy Asthma Immunol. 2001, v. 86 (1), p. 68-70.
- Погомий Н.Н., Пампура А.Н., Чернова О.И. и соавт. Роль сульфитных соединений в течении бронхиальной астмы и атопического дерматита у детей. Российский вестник перинатологии и педиатрии. 1998, № 6, с. 15-19.
- Merget R., Sander I., Rozynek P. et al. Occupational hypersensitivity pneumonitis due to molds in an onion and potato sorter. Am. J. Ind. Med. 2008, v. 51 (2), p. 117-119.
- De Swert L.F., Cadot P., Ceuppens J.L. Diagnosis and natural course of allergy to cooked potatoes in children. Allergy. 2007, v. 62 (7), p. 750-757.
- Dreborg S., Foucard T. Allergy to apple, carrot and potato in children with birch pollen allergy. Allergy. 1983, v. 38 (3), p. 167-172.
- Sanchez Palacios A. Latex allergy. Diagnosis and therapeutic aspects. [Spanish] Allergol. Immunopathol. (Madr.). 2001, v. 29 (5), p. 212-221.
- Beezhold D.H., Sussman G.L., Liss G.M., Chang N.S. Latex allergy can induce clinical reactions to specific foods. Clin. Exp. Allergy. 1996, v. 26 (4), p. 416-422.
- Asero R., Mistrello G., Roncarolo D., Amato S. Detection of some safe plant-derived foods for LTP-allergic patients. Int. Arch. Allergy Immunol. 2007, v. 144 (1), p. 57-63.
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