(Non)dangerous antiseptic. Clinical case of confirmed drug allergy to chlorhexidine
- Authors: Pinchuk A.V.1, Myasnikova T.N.1, Latysheva E.A.1
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Affiliations:
- National Research Center — Institute of Immunology Federal Medical-Biological Agency of Russia
- Issue: Vol 22, No 4 (2025)
- Pages: 432-437
- Section: Case reports
- URL: https://journal-vniispk.ru/raj/article/view/375450
- DOI: https://doi.org/10.36691/RJA17047
- EDN: https://elibrary.ru/TGBSOK
- ID: 375450
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Abstract
One of the leading problems in modern allergology is drug hypersensitivity. There is an increase in allergic reactions to medications that are commonly used in routine practice.
The article presents a clinical case of a patient who developed anaphylaxis following the simultaneous administration of local anesthetics and chlorhexidine. Data on drug allergy to antiseptic agents are discussed. As a part of diagnostic workup in vitro and in vivo testing with suspected drugs was conducted, resulting in confirmation of drug allergy to chlorhexidine, which led to the prohibition of its use and ruled out allergy to local anesthetics.
Keywords
About the authors
Anastasiya V. Pinchuk
National Research Center — Institute of Immunology Federal Medical-Biological Agency of Russia
Author for correspondence.
Email: AVPin13@yandex.ru
ORCID iD: 0009-0009-7472-8284
MD
Russian Federation, MoscowTatyana N. Myasnikova
National Research Center — Institute of Immunology Federal Medical-Biological Agency of Russia
Email: t_miasnikova@mail.ru
ORCID iD: 0000-0001-8491-195X
SPIN-code: 4684-3112
MD, Cand. Sci. (Medicine)
Russian Federation, MoscowElena A. Latysheva
National Research Center — Institute of Immunology Federal Medical-Biological Agency of Russia
Email: ealat@mail.ru
ORCID iD: 0000-0002-1606-205X
SPIN-code: 2063-7973
MD, Dr. Sci. (Medicine)
Russian Federation, MoscowReferences
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