The effect of overweight and obesity on the severity of manifestations of chronic nonbacterial prostatitis with an inflammatory component
- Authors: Amelchenko A.A.1,2, Vinnik Y.Y.1,3
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Affiliations:
- Krasnoyarsk State Medical University named after prof. V.F. Voino-Yasenetsky
- Krasnoyarsk Interdistrict Clinical Hospital No. 4
- Krasnoyarsk Regional Dermatovenerological Dispensary No. 1
- Issue: Vol 14, No 1 (2024)
- Pages: 15-22
- Section: Original articles
- URL: https://journal-vniispk.ru/uroved/article/view/257394
- DOI: https://doi.org/10.17816/uroved623501
- ID: 257394
Cite item
Abstract
BACKGROUND: Chronic prostatitis is one of the most common urological diseases of young and middle-aged men. The variety of pathogenetic mechanisms and clinical manifestations, the tendency to recurrence necessitates the search for new methods of examination and monitoring of this disease.
AIM: To identify the characteristics of the clinical manifestations of chronic non-bacterial prostatitis with an inflammatory component in men of the first period of adulthood, depending on the body mass index.
MATERIALS AND METHODS: A comprehensive urological examination was carried out on 150 men with CNVC in the first period of adulthood, aged 22 to 35 years. All patients were assessed for hormonal status, as well as anthropometric parameters.
RESULTS: Men with normal body mass index had milder clinical symptoms of prostatitis compared with overweight and obese patients. The results of laboratory studies demonstrated a more pronounced inflammatory process and dysfunction of the prostate in patients with a higher body mass index. Analysis of hormonal status revealed high levels of total and free testosterone and low levels of estradiol in men with normal body mass index. The content of sex hormone-binding globulin was significantly lower in obese patients. Overweight and obese men also had larger prostate volume according to TRUS.
CONCLUSIONS: More severe manifestations of prostatitis are associated with an increase in body mass index.
Keywords
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##article.viewOnOriginalSite##About the authors
Andrei A. Amelchenko
Krasnoyarsk State Medical University named after prof. V.F. Voino-Yasenetsky; Krasnoyarsk Interdistrict Clinical Hospital No. 4
Author for correspondence.
Email: aroun88@yandex.ru
ORCID iD: 0000-0003-2867-4317
SPIN-code: 6601-4370
Assistent, Department of Urology, Andrology and Sexology of the Institute of Postgraduate Education, Urologist
Russian Federation, Krasnoyarsk; KrasnoyarskYurii Yu. Vinnik
Krasnoyarsk State Medical University named after prof. V.F. Voino-Yasenetsky; Krasnoyarsk Regional Dermatovenerological Dispensary No. 1
Email: vinnik33@mail.ru
ORCID iD: 0000-0002-8135-0445
SPIN-code: 7946-6230
MD, Dr. Sci. (Medicine)
Russian Federation, 1 Partizana Zheleznyaka st., Krasnoyarsk, 660022; KrasnoyarskReferences
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