Medical Materials Based on Chitosan Succinamide–Glycerol Systems

M. V. Bazunova; L. A. Sharafutdinova; R. Yu. Lazdin; V. V. Chernova; D. N. Mixonov; V. P. Zakharov

doi:10.1134/S0003683818050058

Medical Materials Based on Chitosan Succinamide–Glycerol Systems

Authors: Bazunova M.V.¹, Sharafutdinova L.A.¹, Lazdin R.Y.¹, Chernova V.V.¹, Mixonov D.N.¹, Zakharov V.P.¹
Affiliations:
1. Bashkir State University
Issue: Vol 54, No 5 (2018)
Pages: 474-477
Section: Article
URL: https://journal-vniispk.ru/0003-6838/article/view/152579
DOI: https://doi.org/10.1134/S0003683818050058
ID: 152579

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Abstract

The conditions to obtain materials with elastic-viscous properties based on chitosan succinamide have been studied. A decreased polymer content and a transition from visco-elastic liquids to elastic-viscous systems were shown upon the addition of glycerol to an aqueous solution of chitosan succinamide. The systemic response, biological compatibility, and dynamics of bioresorbability of the obtained materials were studied during implantation in laboratory animals.