Biocompatible Nanomaterial for Restoration of Continuity of Dissected Biological Tissues

Abstract

A technology for manufacturing biocompatible nanomaterials for laser restoration of the continuity of dissected fragments of biological tissue (cattle trachea) was described. The tensile strength of laser welds obtained by laser irradiation of biocompatible nanomaterial deposited on the edges of dissected tissues was studied. The maximum tensile strength of laser welds of ~0.196 MPa was achieved using a biocompatible nanomaterial consisting of albumin (25 wt. %), collagen (1 wt. %), multi-walled carbon nanotubes (1 wt. %), and the indocyanine green dye (0.1 wt. %). The biocompatibility of the nanomaterial was studied using the MTT assay. The biocompatible nanomaterial exerted the best effect on the proliferative activity of cells when diluted in the culture medium to concentrations of 1/10, 1/20, 1/160 and 1/320.