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Vol 53, No 2 (2019)

Theory and Design

Experimental Validation of a Numerical Model of an Axial Circulatory Assist Blood Pump

Gouskov A.M., Sorokin F.D., Banin E.P., Krupnin A.E., Skoryukov S.V.

Abstract

This study continues our systematic exploration of the design of an axial circulatory assist blood pump with a rotor on magnetic bearings. The work reported here addresses experimental validation of a numerical model of flow in the flow part of the axial blood pump. The study focuses on design of the test rig, design of experiments, and modeling of blood flow in the flow part of the pump using computational fluid dynamics. The working fluid was distilled water. The flow-pressure characteristics obtained experimentally were compared with those from mathematical modeling. A satisfactory agreement between the results was obtained, such that the mathematical model can be used for future simulation of the operation of the pump and further optimization of the main components.

Biomedical Engineering. 2019;53(2):77-81
pages 77-81 views

Article

The Effect of a Hyperpolarization Pulse on a Model of Cardiomyocyte under Fibrillation Conditions

Gorbunov B.B., Selishchev S.V.

Abstract

The effect of a hyperpolarization pulse on a model of cardiomyocyte under simulated fibrillation conditions was studied.

Biomedical Engineering. 2019;53(2):82-86
pages 82-86 views

Microwave Radiometry in the Diagnosis of Various Urological Diseases

Kaprin A.D., Kostin A.A., Andryukhin M.I., Ivanenko K.V., Popov S.V., Shegai P.V., Kruglov D.P., Mangutov F.S., Leushin V.Y., Agasieva S.V.

Abstract

Microwave radiometry is based on measurement of the intrinsic electromagnetic irradiation of a patient’s internal tissues in the ultra-high frequency range. It is used with success in clinical practice. Results of studies of the diagnostic potential of microwave radiometry in different forms of acute pyelonephritis, renal colic, and acute inflammatory diseases of the prostate have demonstrated its informativeness and safety and have determined the value of this method in complex (including early) diagnosis and for monitoring of treatment efficacy. Use of microwave radiometry has been shown to reduce the number of errors and to increase the informativeness of existing X-ray and ultrasound diagnostic methods at the early stages of acute inflammatory diseases of the kidneys and prostate.

Biomedical Engineering. 2019;53(2):87-91
pages 87-91 views

A Thermoelectric Device to Stop Bleeding

Ismailov T.A., Yevdulov O.V., Ragimova T.A., Nabiev N.A.

Abstract

The design of a device for stopping bleeding is considered, in which the operative element is a thermoelectric battery (TEB) operating in cooling mode until the moment at which bleeding stops and in heating mode when the device is removed from the damage site. A model of the device based on solving the problem of thermal conductivity on phase transition is proposed. Numerical experimental results yielded a relationship between the time taken to form solid-phase blood 3 mm thick and the power and supply current of the TEB at different blood flow pressures in the wound zone. The device can use a standard TEB with power consumption of 40_80 W depending on the area of blood flow for procedures lasting 7-8 min.

Biomedical Engineering. 2019;53(2):92-96
pages 92-96 views

Comparison of Filtering Techniques in Ultrasound Color Flow Imaging

Leonov D.V., Kulberg N.S., Fin V.A., Podmoskovnaya V.A., Ivanova L.S., Shipaeva A.S., Vladzimirskiy A.V., Morozov S.P.

Abstract

The article considers filtering techniques used to suppress clutter signals from moving tissues and to improve reliability of blood flow estimation. It compares polynomial and adaptive bases such as the result of empirical mode decomposition and singular vectors obtained through Karhunen−Loève transform. Filtering techniques are examined using a computer-simulated model, Doppler flow phantom and in vivo data. Filters are compared in terms of computational complexity, ability to retrieve flow profile without errors and through ROC curve analysis. Polynomial regression filters with tissue phase shift compensation were found to be the best fit for clutter suppression in terms of computational demands and accuracy of velocity estimation.

Biomedical Engineering. 2019;53(2):97-101
pages 97-101 views

Time–Frequency Analysis of Electroencephalograph Signals Using the Hilbert–Huang Transform

Tychkov A.Y.

Abstract

This article proposes a new use of the Hilbert−Huang transform (HHT) in the preliminary processing and analysis of EEG signals. EEG signal recordings are analyzed using HHT to study patterns of changes in patients with mental disorders. Variants of EEG signals in different coordinate systems are analyzed. Results from analysis of EEG signals demonstrated a relationship between the amplitude−time parameters of HHT and the presence of mental disorders in patients.

Biomedical Engineering. 2019;53(2):102-107
pages 102-107 views

Use of Multichannel Microwave Radiometry for Functional Diagnostics of the Brain

Gudkov A.G., Leushin V.Y., Sidorov I.A., Vesnin S.G., Porokhov I.O., Sedankin M.K., Agasieva S.V., Chizhikov S.V., Gorlacheva E.N., Lazarenko M.I., Shashurin V.D.

Abstract

The results of the development and testing of an experimental model of a noninvasive system for functional diagnostics of the brain based on the principles of multichannel microwave radiometry are presented.

Biomedical Engineering. 2019;53(2):108-111
pages 108-111 views

Intraoperative Multispiral Computerized Tomography in the Surgical Treatment of Intradural Spinal Cord Tumors

Byvaltsev V.A., Stepanov I.A., Aliev M.A.

Abstract

This article addresses a novel technical solution in the surgical treatment of intradural spinal cord tumors – the use of intraoperative multispiral computerized tomography (IMSCT). The IMSCT method, as compared with pre-operative magnetic resonance tomograms, provides clear determination of tumor position levels and provides for minimization of the volumes of soft tissue dissection and bone resection, thus reducing the risk of various adverse events. This intraoperative navigation method can be recommended for use in the surgical treatment of intradural spinal cord tumors (IDSCT).

Biomedical Engineering. 2019;53(2):112-116
pages 112-116 views

New Principles in the Operation of Neural Emulators in Medical Diagnosis

Khromushin V.A., Pyatin V.F., Eskov V.V., Ilyashenko L.K., Vokhmina Y.V.

Abstract

Despite ever wider use of neural computers (NC) and their simulators − neural emulators − in medicine, their further use comes up against the fundamental impossibility of using them to solve tasks of systemic synthesis (finding the most important diagnostic signs, \( {x}_i^{\ast } \), in medicine). This article presents two new principles (the chaotic organization of the initial state of weightings Wi0 of xi features and the principle of multiple reverberations), which can be solved using NC for systemic synthesis. Examples of the use of such special operating modes in cardiovascular physiology are presented. Uncertainties of types 1 and 2 in medicine are considered; these cannot be resolved within the framework of stochastics.

Biomedical Engineering. 2019;53(2):117-120
pages 117-120 views

Determination of X-Ray Beam Characteristics from the Secondary Radiation Field Profile

Lelyukhin A.S.

Abstract

A new method for determining the anode voltage and the total filtration of X-ray diagnostic devices from the profile of secondary radiation fields is proposed. Secondary radiation fields are excited near a composite scattering body made of materials with different absorption properties. It is shown that the asymmetry coefficient and the lower quartile of the experimentally recorded distributions can be used as measurement criteria.

Biomedical Engineering. 2019;53(2):121-124
pages 121-124 views

Effects of Ionizing Radiation Detector Characteristics on the Results of Measurements of Percent Depth Doses in Small Photon Fields

Klenevskii A.V., Bogatov N.M.

Abstract

Studies of the dosimetric parameters of small fields of ionizing radiation are extremely important in current clinical dosimetry. This article considers analysis of plots of percent depth dose in small photon fields obtained using an Elekta Synergy medical linear electron accelerator with energies of 6 and 10 MeV using ionization chambers with different active volumes and a semiconductor detector. Comparative data for the following parameters are presented: depth of maximum dose, surface dose, dose at a depth of 10 cm, and various other aspects of the plots. These data were found to depend on the type of detector used in identical measurement conditions. The main features of the detection of dose distributions by different detectors are noted and conclusions are drawn regarding the advantages of using detectors with the smallest available active volumes in clinical dosimetry.

Biomedical Engineering. 2019;53(2):125-129
pages 125-129 views

A Portable Device for Laser-and-Ultrasound Therapy: Design and Application

Nikitin V.A., Vasil’eva L.V., Popov A.V.

Abstract

The design and functional capabilities of the portable device for laser-and-ultrasound therapy BINOM®-FIZIO LUZT are described together with the experience of its use for treating patients with chronic obstructive lung disease (COLD). Infrared laser pulses and ultrasound generated by an array of sources are the therapeutic agents used for treatment. The developed device makes it possible to implement a new physical therapy technique for simultaneous (concomitant) treatment with low-intensity laser radiation and ultrasound. Clinical tests showed the device to be cost-effective and improve the clinical effect of combination treatment. It allows better expectoration, peripheral blood parameters, and respiratory function to be achieved.

Biomedical Engineering. 2019;53(2):130-133
pages 130-133 views

Pulse Wave Sensor Sensitivity to Changing the Point of Measurement

Yavelov I.S., Stepanyan I.V., Rochagov A.V., Zholobov A.V., Yavelov R.I., Yavelov O.I.

Abstract

A method for measuring the pulse wave on the wrist based on a multipoint sensor with a fiber-optic transducer probe is proposed. The development and current state of techniques for recording the radial artery pulse wave signal are analyzed. It is noted that the problem of comfortable pulse wave detection without reinstalling the sensor has not yet been solved. The possibility of reducing the distortions in the pulse wave signal using the method of superposition of readings of reinstalled single-point sensor is considered. It was shown experimentally that at any position of the proposed sensor it is possible to reliably measure the pulse wave signal. Amplitude changes in the measuring channels corresponding to the displacement of the radial artery apex relative to the sensor could be traced in the recordings. Thus, it can be concluded that it is possible to design a mobile medical device for comfortable measurement of the pulse wave, which does not require special skills when installing the sensor. A name for such a device − matrix analyzer of pulse wave (MAPW) − is suggested.

Biomedical Engineering. 2019;53(2):134-136
pages 134-136 views

Strength Characteristics of the Bone−Implant−Bone System in Midshaft Clavicular Fracture Osteosynthesis

Minasov B.S., Yakupov S.F., Yakupov R.R., Bilyalov A.R., Valeev M.M., Minasov Т.B., Mavlyutov Т.R., Nagimov M.I., Garipov I.I.

Abstract

A method of surgical treatment of midshaft clavicular fractures and a compression interlocking nail for osteosyn-thesis of the clavicle were developed. Strength characteristics of various bone−implant−bone systems in osteosyn-thesis of midshaft clavicular fractures were compared. It was shown that none of the tested fixation techniques provides stability under conditions of axial loading comparable to that of an intact clavicle. The developed design can be recommended as a method of choice for osteosyn-thesis of midshaft clavicular fractures, as it demonstrated strength characteristics comparable to those of other systems.

Biomedical Engineering. 2019;53(2):137-141
pages 137-141 views

A Method for Estimating the Degree of Ischemic Damage to the Anatomical Zones of the Lower Limbs from the Parameters of Hemostasis and Blood Supply

Bykov A.V., Korenevskiy N.A., Khubulava G.G., Khripina I.I., Rodionova S.N.

Abstract

The methodology of synthesis of hybrid fuzzy decision rules was used to obtain mathematical models for classi-fying ischemic lesions of the lower limbs into four classes of severity based on a group of rheological indices (D-dimer, leukocytes, platelets, fibrinogen), volume blood flow velocity, and regional systolic blood pressure. Rational treatment regimens were determined for each of the classes. The introduction of the proposed models and treatment regimens into medical practice would make it possible to reduce the number of amputations by 65% and to improve the social adaptation and life quality of 80% of patients with critical lower limb ischemia.

Biomedical Engineering. 2019;53(2):142-145
pages 142-145 views

Surgical Stereo X-Ray Navigation

Nazaruk V.P., Nechaev A.I., Potrakhov N.N., Chernakova S.E.

Abstract

Hardware and software for surgical instrument navigation using stereo X-ray imaging were developed. The developed surgical stereo X-ray navigation system provides 3D imaging in the process of surgery or during diagnostic examination of deep-lying abnormal foci or structural abnormalities of organs and tissues. Application of the developed system makes it possible to reduce considerably the duration of surgery. The obtained 3D X-ray images are automatically processed to provide accurate real-time guidance of the medical instrument (i.e., adjustment of the penetration depth, position, and orientation of the instrument). The developed technique of stereo X-ray navigation can be used for purposes of upgrading medical X-ray equipment, such as C-arch (Arcoscope) surgical X-ray devices.

Biomedical Engineering. 2019;53(2):146-151
pages 146-151 views