Developmental features of cerebrovascular reaction to functional tests as revealed by transcranial Doppler sonography


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Abstract

The paper addresses developmental features of the cerebrovascular reaction to functional tests as studied in volunteers of different ages without any signs of cerebrovascular pathology. Using transcranial Doppler sonography, it was shown that a significant decrease in the degree of manifestation of the cerebrovascular response to dosated functional loads occurs with age. A study of developmental features of this reaction to functional tests caused by autonomic regulation allowed distinguishing four types of its implementation: highly reactive, reactive, areactive and paradoxical. The data obtained support the informational significance of transcranial Doppler sonography and cerebrovascular reactivity for the identification of early changes in the state of the cerebrovascular system and its adaptive and compensatory abilities.

About the authors

Yu. E. Moskalenko

Sechenov Institute of Evolutionary Physiology and Biochemistry

Email: Julia-andr@bk.ru
Russian Federation, St. Petersburg

Yu. V. Andreeva

Sechenov Institute of Evolutionary Physiology and Biochemistry

Author for correspondence.
Email: Julia-andr@bk.ru
Russian Federation, St. Petersburg

A. A. Panov

Sechenov Institute of Evolutionary Physiology and Biochemistry

Email: Julia-andr@bk.ru
Russian Federation, St. Petersburg

V. N. Semernya

Sechenov Institute of Evolutionary Physiology and Biochemistry

Email: Julia-andr@bk.ru
Russian Federation, St. Petersburg

M. A. Sabirov

Sechenov Institute of Evolutionary Physiology and Biochemistry

Email: Julia-andr@bk.ru
Russian Federation, St. Petersburg

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