Osseointegration after local cryotherapy
- 作者: Shakurov A.V.1, Skryabin A.S.1, Lukina Y.S.1
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隶属关系:
- Bauman Moscow State Technical University
- 期: 卷 111, 编号 4 (2022)
- 页面: 279-282
- 栏目: Short Communications
- URL: https://journal-vniispk.ru/0023-124X/article/view/132752
- DOI: https://doi.org/10.17816/RF114718
- ID: 132752
如何引用文章
详细
This study aims to analyze the prospects for using local cryotherapy in bone remodeling. Intense cooling causes a response. To evaluate the effectiveness of the cryostimulation of a bone defect in the in vivo model of Wistar rats, defects 2 mm in diameter were formed. The animals were subjected to cryotherapy once or twice a week. The average local temperature of the skin surface decreased from 28 to 14 °C. The temperature inside the biological tissue near the bone defect decreased by 5 °C. Microcomputer tomography and histological analysis showed that a semiweekly cryotherapy is an effective approach. The results showed the promise of using low temperatures in the complex treatment of injuries and bone diseases. This information will be useful for understanding the correlation of the effect and impact of cryostimulation as well as for developing treatment protocols, allowing us to progress toward the possibility of using cryostimulation in practical bone healing.
作者简介
Alexey Shakurov
Bauman Moscow State Technical University
编辑信件的主要联系方式.
Email: shakurov@bmstu.ru
ORCID iD: 0000-0001-6110-8101
SPIN 代码: 1894-4707
Cand. Sci. (Tech.), Associate Professor
俄罗斯联邦, MoscowAndrey Skryabin
Bauman Moscow State Technical University
Email: terra107@yandex.ru
ORCID iD: 0000-0002-8578-2632
SPIN 代码: 3286-8502
Cand. Sci. (Tech.)
俄罗斯联邦, MoscowYulia Lukina
Bauman Moscow State Technical University
Email: lukina_rctu@mail.ru
ORCID iD: 0000-0003-0121-1232
SPIN 代码: 2814-7745
Cand. Sci. (Tech.)
俄罗斯联邦, Moscow参考
- Castano D, Comeau-Gauthier M, Ramirez-Garcia Luna JL, et al. Noninvasive localized cold therapy: a new mode of bone repair enhancement. Tissue Engineering Part A. 2019;25(7–8):554–562. doi: 10.1089/ten.tea.2018.0191
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