The impact of intradermal injections of modified hyaluronic acid on the morphological skin condition in female patients with involutional changes

Goal. To provide a clinical assessment of the efficacy and tolerance of hyaluronic acid (HA) drugs modified with vitamin С and amino acids in patients with involutional skin changes. Methods. As many as 90 female patients underwent a course of treatment for age-related skin changes including three procedures of intradermal injections of modified HA. The skin condition was assessed prior to and after the treatment by using non-invasive methods (corneometry, pH-metry, sebometry, elastometry, visio-scanning, ultrasonic derma-scanning and confocal laser scanning microscopy). Results. The authors demonstrated good tolerance of modified HA and skin condition improvement (better elasticity, moisture level, improvement of the skin structure and microrelief, reduction in the intensity of expression and static wrinkles, restoration of color uniformity and elimination of xerosis manifestations). Conclusion. The study results are sufficient to recommend modified HA drugs for correcting involutional skin changes.

modified hyaluronic acid, biorepair agents, involutional skin changes, non-invasive skin diagnostics