Determination of active substances and pharmacoeconomic value of bergenia pacifica
- Authors: Igorevna S.K.1, Korochkina T.V.1, Menzorov K.A.1, Krasnyuk I.I.1, Zubareva I.M.1, Korochkin M.D.1, Bobkova N.V.1
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Affiliations:
- I.M. Sechenov First Moscow State Medical University of the Ministry of Health f the Russian Federation (Sechenov University)
- Issue: Vol 74, No 6 (2025)
- Pages: 14-24
- Section: Pharmaceutical chemistry and pharmacognosy
- URL: https://journal-vniispk.ru/0367-3014/article/view/316988
- DOI: https://doi.org/10.29296/25419218-2025-06-02
- ID: 316988
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Abstract
Introduction. The pharmacological potential of medicinal plants is a valuable but often underutilized resource in modern pharmaceuticals. Bergenia pacifica from the Saxifragaceae family is an example of such a phenomenon – a plant with significant therapeutic capabilities, the spectrum of therapeutic action of which has not yet been fully determined and continues to actively expand.
The aim of the study. A comprehensive assessment of the pharmacological potential of Bergenia pacifica and its active component bergenin, possible therapeutic applications and determination of the pharmacoeconomic value of the raw material.
Material and methods. In the course of this study, an analysis of open databases of scientific domestic and foreign literary sources on the use of Bergenia pacifica and its active ingredient bergenin as a medicinal herbal remedy was carried out, including methods for qualitative, quantitative determination, and assessment of the pharmacoeconomic value of this raw material.
Results. In open databases of scientific literature, the keywords “bergenia pacifica”, “pacifica”, “бадан тихоокеанский” contain about 170 mentions, 37 targeted studies and 35 patents. There are 662 mentions of keywords containing “bergenin”. In all the literature sources found, Pacific badan and its active ingredient bergenin are defined as herbal medicines.
Conclusion. Thus, the widespread use of Bergenia pacifica and its active ingredient bergenin in medicine as a medicinal herbal remedy determines its potential as a raw material base for the development of new medicines and the improvement of technologies for processing plant raw materials, which requires experimental and clinical research in the future.
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##article.viewOnOriginalSite##About the authors
Svetlana Kosenkova Igorevna
I.M. Sechenov First Moscow State Medical University of the Ministry of Health f the Russian Federation (Sechenov University)
Author for correspondence.
Email: sv-omega@yandex.ru
ORCID iD: 0000-0001-9337-5917
Candidate of Pharmaceutical Sciences, Lecturer, Department of Pharmaceutical Technology, A.P. Nelyubin Institute of Pharmacy
Russian Federation, Mosсow, 119991, Trubetskaya str., 8/2Tatiana Viktorovna Korochkina
I.M. Sechenov First Moscow State Medical University of the Ministry of Health f the Russian Federation (Sechenov University)
Email: fourkor@mail.ru
ORCID iD: 0000-0002-0944-1510
Senior Lecturer, Department of Pharmaceutical Technology, A.P. Nelyubin Institute of Pharmacy
Russian Federation, Mosсow, 119991, Trubetskaya str., 8/2Kirill Antonovich Menzorov
I.M. Sechenov First Moscow State Medical University of the Ministry of Health f the Russian Federation (Sechenov University)
Email: kirill.menzorov073@gmail.com
ORCID iD: 0009-0009-3870-9764
Resident, Department of Pharmaceutical Technology of the A.P. Nelyubin Institute of Pharmacy
Russian Federation, Mosсow, 119991, Trubetskaya str., 8/2Ivan Ivanovich Krasnyuk
I.M. Sechenov First Moscow State Medical University of the Ministry of Health f the Russian Federation (Sechenov University)
Email: krasnyuki@mail.ru
ORCID iD: 0000-0002-7242-2988
Doctor of Pharmaceutical Sciences, Professor of the Department of Pharmaceutical Technology at the A.P. Nelyubin Institute of Pharmacy
Russian Federation, Mosсow, 119991, Trubetskaya str., 8/2Irina Mikhailovna Zubareva
I.M. Sechenov First Moscow State Medical University of the Ministry of Health f the Russian Federation (Sechenov University)
Email: irina.kashlikova@mail.ru
ORCID iD: 0000-0002-0367-214X
Candidate of Pharmaceutical Sciences, Associate Professor of the Department of Pharmaceutical Technology at the A.P. Nelyubin Institute of Pharmacy
Russian Federation, Mosсow, 119991, Trubetskaya str., 8/2Maria Dmitrievna Korochkin
I.M. Sechenov First Moscow State Medical University of the Ministry of Health f the Russian Federation (Sechenov University)
Email: korochkina_m_d@student.sechenov.ru
ORCID iD: 0000-0002-2790-9041
Student, A.P. Nelyubin Institute of Pharmacy
Russian Federation, Mosсow, 119991, Trubetskaya str., 8/2Natalia Vladimirovna Bobkova
I.M. Sechenov First Moscow State Medical University of the Ministry of Health f the Russian Federation (Sechenov University)
Email: bobkova_n_v_1@staff.sechenov.ru
ORCID iD: 0000-0003-1591-4019
Candidate of Pharmaceutical Sciences, Professor of the Department of Pharmaceutical Natural Sciences, A.P. Nelyubin Institute of Pharmacy
Russian Federation, Mosсow, 119991, Trubetskaya str., 8/2References
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