Suspension-cultured plant cells as a platform for obtaining recombinant proteins
- Authors: Zagorskaya A.A.1, Deineko E.V.1,2
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Affiliations:
- Institute of Cytology and Genetics, Siberian Branch
- National Research Tomsk State University
- Issue: Vol 64, No 6 (2017)
- Pages: 795-807
- Section: Reviews
- URL: https://journal-vniispk.ru/1021-4437/article/view/179847
- DOI: https://doi.org/10.1134/S102144371705017X
- ID: 179847
Cite item
Abstract
Production of recombinant proteins in suspension cultures of genetically modified plant cells is a promising and rapidly developing area of plant biotechnology. In the present review article, advantages related to using plant systems for expression of recombinant proteins are considered. Here, the main focus is covering the literature on optimization of cultivation conditions of suspension-cultured plant cells to obtain a maximal yield of target proteins. In particular, certain examples of successful use of such cells to produce pharmaceuticals were described.
About the authors
A. A. Zagorskaya
Institute of Cytology and Genetics, Siberian Branch
Author for correspondence.
Email: zagorska@bionet.nsc.ru
Russian Federation, Novosibirsk
E. V. Deineko
Institute of Cytology and Genetics, Siberian Branch; National Research Tomsk State University
Email: zagorska@bionet.nsc.ru
Russian Federation, Novosibirsk; Tomsk
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