GENERATION AND CHARACTERIZATION OF RECOMBINANT ANTIBODY AGAINST THE COMPLEMENT C5a ANAPHYLATOXIN
- Authors: Vasilishina A.A.1, Demyanov A.V.1, Monahova V.S.1, Zhakhov A.V.1, Trofimov A.V.1, Denisenko E.S.1, Nekrasova K.A.1, Rodin S.V.1, Simbirtsev A.S.1, Ischenko A.M.1
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Affiliations:
- State Research Institute of Highly Pure Biopreparations
- Issue: Vol 22, No 2-2 (2019)
- Pages: 728-730
- Section: ORIGINAL ARTICLES
- URL: https://journal-vniispk.ru/1028-7221/article/view/119438
- DOI: https://doi.org/10.31857/S102872210006722-9
- ID: 119438
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About the authors
A. A. Vasilishina
State Research Institute of Highly Pure Biopreparations
Author for correspondence.
Email: a.a.vasilishna@hpb.spb.ru
MD, Biologist of Laboratory of Protein Biochemistry,
Saint Petersburg
Russian FederationA. V. Demyanov
State Research Institute of Highly Pure Biopreparations
MD, Head of Laboratory of Immunopharmacology,
Saint Petersburg
Russian FederationV. S. Monahova
State Research Institute of Highly Pure Biopreparations
Biologist, Laboratory of Protein Biochemistry,
Saint Petersburg
Russian FederationA. V. Zhakhov
State Research Institute of Highly Pure Biopreparations
Leading Researcher, Laboratory of Protein Biochemistry,
Saint Petersburg
Russian FederationA. V. Trofimov
State Research Institute of Highly Pure Biopreparations
Group Leader, Laboratory of Protein Biochemistry,
Saint Petersburg
Russian FederationE. S. Denisenko
State Research Institute of Highly Pure Biopreparations
Project Manager,
Saint Petersburg
Russian FederationK. A. Nekrasova
State Research Institute of Highly Pure Biopreparations
Deputy Head of R&D Department,
Saint Petersburg
Russian FederationS. V. Rodin
State Research Institute of Highly Pure Biopreparations
Group Leader, Laboratory of Protein Biochemistry,
Saint Petersburg
Russian FederationA. S. Simbirtsev
State Research Institute of Highly Pure Biopreparations
RAS Corresponding Member, DMedSci, Professor, Scientific Supervisоr,
Saint Petersburg
Russian FederationA. M. Ischenko
State Research Institute of Highly Pure Biopreparations
PhD, Head of Laboratory of Protein Biochemistry,
Saint Petersburg
Russian FederationReferences
- Chunguang Yan, Hongwei Gao. New insights for C5a and C5a receptors in sepsis. Front Immunol. 2012, 5, 197.
- Aird W. C. The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome. Blood. 2003, 101, 3765–3777.
- Peter A. Ward Role of C5 Activation Products in Sepsis. The Scientific World Journal. 2010, 10, 2395– 24022010.
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