CONTENT OF ENDOTHELIAL PROGENITOR CELLS IN UMBILICAL CORD BLOOD IN PREECLAMPSIA
- 作者: Popova I.G.1, Nazarov S.B.1, Kuzmenko G.N.1, Kroshkina N.V.1, Sitnikova O.G.1, Klycheva M.M.1
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隶属关系:
- Ivanovo research Institute of Maternity and Childhood V. N. Gorodkova
- 期: 卷 22, 编号 2-2 (2019)
- 页面: 897-899
- 栏目: ORIGINAL ARTICLES
- URL: https://journal-vniispk.ru/1028-7221/article/view/119864
- DOI: https://doi.org/10.31857/S102872210006550-0
- ID: 119864
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详细
The content of endothelial progenitor cells in umbilical cord blood was determined in newborns born to mothers with preeclampsia and without preeclampsia. Phenotyping of umbilical cord blood endothelial cells was performed by flow cytometry, circulating endothelial cells (CES) were defined as: CD45–, CD133+, VEGFR2+, CD34–, endothelial progenitor cells (EPCS) were defined as: CD45–, CD133+, VEGFR2+, CD34+. There was a decrease in both the total number of circulating endothelial cells and endothelial progenitor cells in premature infants compared to full-term ones. In newborns born to mothers with preeclampsia, only the number of ECP was significantly higher, compared with newborns from mothers without preeclampsia, and in the group of premature and full-term newborns.
作者简介
I. Popova
Ivanovo research Institute of Maternity and Childhood V. N. Gorodkova
编辑信件的主要联系方式.
Email: i_g_popova@mail.ru
candidate of medical Sciences, researcher of clinical biochemistry laboratory, doctor of clinical laboratory diagnostics,
Ivanovo
俄罗斯联邦S. Nazarov
Ivanovo research Institute of Maternity and Childhood V. N. Gorodkova
Email: fake@neicon.ru
doctor of medical Sciences, рrofessor, Deputy Director of the Institute for scientific work, head. laboratory of clinical biochemistry and genetics,
Ivanovo
俄罗斯联邦G. Kuzmenko
Ivanovo research Institute of Maternity and Childhood V. N. Gorodkova
Email: fake@neicon.ru
doctor of medical Sciences, leading researcher of laboratory of clinical biochemistry, head. clinical diagnostic laboratory,
Ivanovo
俄罗斯联邦N. Kroshkina
Ivanovo research Institute of Maternity and Childhood V. N. Gorodkova
Email: fake@neicon.ru
candidate of biology, researcher at the laboratory of clinical immunology,
Ivanovo
俄罗斯联邦O. Sitnikova
Ivanovo research Institute of Maternity and Childhood V. N. Gorodkova
Email: fake@neicon.ru
candidate of biology, senior researcher of clinical biochemistry and genetics,
Ivanovo
俄罗斯联邦M. Klycheva
Ivanovo research Institute of Maternity and Childhood V. N. Gorodkova
Email: fake@neicon.ru
researcher of clinical biochemistry laboratory,
Ivanovo
俄罗斯联邦参考
- Перфилова В. Н., Михайлова Л. И., Тюренков И. Н. Последствия гестоза (преэклампсии). Российский вестник перинатологии и педиатрии. 2014;2:13–17.
- Paviotti G., Boscaroet E., Fadini G. P., Agostini C. Endothelial progenitor cells, bronchopulmonary dysplasia and other short-term outcomes of extremely preterm birth. Stem Cells. 2011; 87 (7): 461–5.
- Румянцев А. Г., Румянцев С. А. Пуповинная кровь как источник информации о состоянии плода. Педиатрия. 2012; 91(3): 43–52.
- Попова И. Г., Назаров С. Б., Кузьменко Г. Н., Крошкина Н. В., Сотникова Н. Ю., Харламова Н. В. Содержание эндотелиальных клеток-предшественников в пуповинной крови у доношенных и недоношенных новорожденных. Российский вестник перинатологии и педиатрии. 2018; 4(63): 58–62.
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