Email this article THE EVALUATION OF THE EFFECTIVENESS OF LOCAL APPLICATION OF OZONE THERAPY FOLLOWING CRYOTHERAPY OF LESIONS OF VERRUCOUS LEUKOPLAKIA OF THE ORAL MUCOUS MEMBRANE
- Authors: Tokmakova S.I.1, Bondarenko O.V1, Shilova J.N1
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Affiliations:
- Altai State Medical University
- Issue: Vol 22, No 4 (2017)
- Pages: 184-187
- Section: Articles
- URL: https://journal-vniispk.ru/1028-9984/article/view/40361
- DOI: https://doi.org/10.18821/1028-9984-2017-22-4-184-187
- ID: 40361
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Abstract
There are presented results of the study morphological and clinical changes of the oral mucosal membrane. In the experiment on laboratory animals the use of ozone therapy following the destruction of the mucous membrane of the mouth was proved to appear earlier with the more complete epithelization of the defect, compared to the treatment implemented according to the traditional scheme. There was performed a clinical examination of 32 patients with verrucous leukoplakia of the oral mucosal membrane, the treatment of which was carried out according to the traditional scheme (cryotherapy and topical anti-inflammatory treatment - group comparison) and with the use of the ozonized solution of olive oil with a known peroxide during the postoperative period (control group). To assess the effectiveness of the proposed method of the management of the postoperative wound there was used a point scoring system of clinical signs at stages of the postoperative period. There was revealed a more earlier onset of the complete epithelization in cases of the application of the local ozone therapy in comparison with traditional local treatment.
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##article.viewOnOriginalSite##About the authors
Svetlana I. Tokmakova
Altai State Medical University
Email: agmuterst@mail.ru
MD, PhD, DSc, Prof., Head of the Therapeutic Dentistry Department of the Altai State Medical University; Barnaul, 656038, Russian Federation Barnaul, 656038, Russian Federation
O. V Bondarenko
Altai State Medical UniversityBarnaul, 656038, Russian Federation
J. N Shilova
Altai State Medical UniversityBarnaul, 656038, Russian Federation
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