Monodisperse spherical meso–macroporous silica particles: Synthesis and adsorption of biological macromolecules


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Abstract

Monodispersed spherical silica particles, including large mesopores (over 10 nm) and macropores (up to 100 nm) were obtained by chemical etching in an autoclave. A method for introducing globular protein myoglobin molecules into the pores is developed. The method of filling is based on a high adsorption capacity of the developed internal pore structure of the particles. The structure and adsorption properties of the materials are studied.

About the authors

E. Yu. Stovpiaga

Ioffe Institute

Author for correspondence.
Email: kattrof@gvg.ioffe.ru
Russian Federation, St. Petersburg, 194021

S. A. Grudinkin

Ioffe Institute; National Research University of Information Technologies, Mechanics, and Optics

Email: kattrof@gvg.ioffe.ru
Russian Federation, St. Petersburg, 194021; St. Petersburg, 197101

D. A. Kurdyukov

Ioffe Institute

Email: kattrof@gvg.ioffe.ru
Russian Federation, St. Petersburg, 194021

Yu. A. Kukushkina

Ioffe Institute

Email: kattrof@gvg.ioffe.ru
Russian Federation, St. Petersburg, 194021

A. V. Nashchekin

Ioffe Institute

Email: kattrof@gvg.ioffe.ru
Russian Federation, St. Petersburg, 194021

V. V. Sokolov

Ioffe Institute

Email: kattrof@gvg.ioffe.ru
Russian Federation, St. Petersburg, 194021

D. R. Yakovlev

Experimentelle Physik 2

Email: kattrof@gvg.ioffe.ru
Germany, Dortmund, DE-44227

V. G. Golubev

Ioffe Institute

Email: kattrof@gvg.ioffe.ru
Russian Federation, St. Petersburg, 194021

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