Email this article Synthesis of new acridine-9-carboxylic acid derivatives
- Authors: Melyshenkova V.V.1, Kuznetsov D.N.1, Ruchkina A.G.1, Kobrakov K.I.1
-
Affiliations:
- А. N. Kosygin Russian State University “Technologies. Design. Art”, Chair of Organic Chemistry
- Issue: Vol 67, No 5 (2018)
- Pages: 878-883
- Section: Full Articles
- URL: https://journal-vniispk.ru/1066-5285/article/view/242534
- DOI: https://doi.org/10.1007/s11172-018-2152-1
- ID: 242534
Cite item
Open Access
Access granted
Subscription Access
Abstract
New 1,3-dihydroxyacridine-9-carboxylic acids were obtained by Pfitzinger reaction from 2,4,6-trihydroxytoluene (methylphloroglucinol). Their bromination and azo-coupling reactions were studied. Computer simulation was used to determine potential pharmacokinetic and toxic properties of the synthesized compounds.
About the authors
V. V. Melyshenkova
А. N. Kosygin Russian State University “Technologies. Design. Art”, Chair of Organic Chemistry
Email: occd@mail.ru
Russian Federation, 1 ul. Malaya Kaluzhskaya, Moscow, 119991
D. N. Kuznetsov
А. N. Kosygin Russian State University “Technologies. Design. Art”, Chair of Organic Chemistry
Author for correspondence.
Email: occd@mail.ru
Russian Federation, 1 ul. Malaya Kaluzhskaya, Moscow, 119991
A. G. Ruchkina
А. N. Kosygin Russian State University “Technologies. Design. Art”, Chair of Organic Chemistry
Email: occd@mail.ru
Russian Federation, 1 ul. Malaya Kaluzhskaya, Moscow, 119991
K. I. Kobrakov
А. N. Kosygin Russian State University “Technologies. Design. Art”, Chair of Organic Chemistry
Email: occd@mail.ru
Russian Federation, 1 ul. Malaya Kaluzhskaya, Moscow, 119991
Supplementary files
