Synthesis of new trichloromethyl- and alkoxy-substituted pyrido[2,3- d ]pyrimidine derivatives

A. V. Komkov; T. V. Potapova; M. I. Zuev; S. V. Baranin; Yu. N. Bubnov

doi:10.1007/s11172-019-2394-6

Synthesis of new trichloromethyl- and alkoxy-substituted pyrido[2,3-d]pyrimidine derivatives

Authors: Komkov A.V.¹, Potapova T.V.¹, Zuev M.I.¹, Baranin S.V.¹, Bubnov Y.N.¹
Affiliations:
1. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
Issue: Vol 68, No 2 (2019)
Pages: 365-373
Section: Full Articles
URL: https://journal-vniispk.ru/1066-5285/article/view/243255
DOI: https://doi.org/10.1007/s11172-019-2394-6
ID: 243255

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Abstract

A series of new trichloromethyl- and alkoxy-substituted pyrido[2,3-d]pyrimidine derivatives were obtained from trichloromethyl-substituted pyrimidines with vicinal amino and acyl groups synthesized based on the reaction of trichloroacetonitrile with β-diketone diaminomethylidene derivatives.