Enviar artigo por via de e-mail New 1-(2-chloroquinolin-3-yl)-4-dimethylamino-2-(naphthalen-1-yl)-1-phenylbutan-2-ols with antituberculosis activity
- Autores: Omel’kov A.V.1, Fedorov V.E.1, Stepanov A.A.1
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Afiliações:
- Pharm-Sintez
- Edição: Volume 68, Nº 10 (2019)
- Páginas: 1908-1918
- Seção: Full Articles
- URL: https://journal-vniispk.ru/1066-5285/article/view/243507
- DOI: https://doi.org/10.1007/s11172-019-2646-5
- ID: 243507
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Resumo
New 4-dimethylamino-2-(naphthalen-1-yl)-1-phenyl-1-(quinolin-3-yl)butan-2-ols with antituberculosis activity were synthesized. (1R*,2S*)-1-(6-Bromo-2-chloroquinolin-3-yl)-4-dimethylamino-2-(naphthalen-1-yl)-1-phenylbutan-2-ol hydrocitrate exhibiting high antituberculosis activity is in the final stage of clinical trials and is prepared for use in clinical practice.
Sobre autores
A. Omel’kov
Pharm-Sintez
Autor responsável pela correspondência
Email: omelkov@mail.ru
Rússia, Build. 134, 29 ul. Vereyskaya, Moscow, 121357
V. Fedorov
Pharm-Sintez
Email: omelkov@mail.ru
Rússia, Build. 134, 29 ul. Vereyskaya, Moscow, 121357
A. Stepanov
Pharm-Sintez
Email: omelkov@mail.ru
Rússia, Build. 134, 29 ul. Vereyskaya, Moscow, 121357
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