Synthesis and antitumor activity of pyridoxine monoalkenyl derivatives
- 作者: Nguyen T.N.1, Iksanova A.G.1, Lodochnikova O.A.2, Shtyrlin Y.G.1, Pugachev M.V.1, Pavelyev R.S.1
- 
							隶属关系: 
							- Research and Education Center of Pharmacy, Kazan (Volga region) Federal University
- A. E. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center of the Russian Academy of Sciences
 
- 期: 卷 65, 编号 2 (2016)
- 页面: 532-536
- 栏目: Full Articles
- URL: https://journal-vniispk.ru/1066-5285/article/view/237253
- DOI: https://doi.org/10.1007/s11172-016-1333-z
- ID: 237253
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详细
A convenient method for the synthesis of pyridoxine alkenyl derivatives by the Wittig reaction of [(2,8-dimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methyl]triphenylphosphonium chloride with aldehydes was suggested. Some of the compounds obtained exhibit antitumor activity in vitro.
作者简介
T. Nguyen
Research and Education Center of Pharmacy, Kazan (Volga region) Federal University
														Email: Yurii.Shtyrlin@gmail.com
				                					                																			                												                	俄罗斯联邦, 							18 ul. Kremlevskaya, Kazan, 420008						
A. Iksanova
Research and Education Center of Pharmacy, Kazan (Volga region) Federal University
														Email: Yurii.Shtyrlin@gmail.com
				                					                																			                												                	俄罗斯联邦, 							18 ul. Kremlevskaya, Kazan, 420008						
O. Lodochnikova
A. E. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center of the Russian Academy of Sciences
														Email: Yurii.Shtyrlin@gmail.com
				                					                																			                												                	俄罗斯联邦, 							8 ul. Akad. Arbuzova, Kazan, 420088						
Yu. Shtyrlin
Research and Education Center of Pharmacy, Kazan (Volga region) Federal University
							编辑信件的主要联系方式.
							Email: Yurii.Shtyrlin@gmail.com
				                					                																			                												                	俄罗斯联邦, 							18 ul. Kremlevskaya, Kazan, 420008						
M. Pugachev
Research and Education Center of Pharmacy, Kazan (Volga region) Federal University
														Email: Yurii.Shtyrlin@gmail.com
				                					                																			                												                	俄罗斯联邦, 							18 ul. Kremlevskaya, Kazan, 420008						
R. Pavelyev
Research and Education Center of Pharmacy, Kazan (Volga region) Federal University
														Email: Yurii.Shtyrlin@gmail.com
				                					                																			                												                	俄罗斯联邦, 							18 ul. Kremlevskaya, Kazan, 420008						
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