Synthesis and biological activity of 3-guanidino-6-R-imidazo[1,2-b]- and 6-guanidino-3-R-[1,2,4]triazolo[4,3-b][1,2,4,5]tetrazines
- 作者: Ishmetova R.I.1, Ignatenko N.K.1, Korotina A.V.1, Ganebnykh I.N.1, Slepukhin P.A.1,2, Babkova V.A.3, Gerasimova N.A.4, Evstigneeva N.P.4, Zilberberg N.V.4, Kungurov N.V.4, Rusinov G.L.1,2, Spasov A.A.3, Chupakhin O.N.1,2
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隶属关系:
- I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
- Ural Federal University named after the first President of Russia B. N. Yeltsin
- Volgograd State Medical University, Ministry of Health of the Russian Federation
- Ural Research Institute of Dermatovenereology and Immunopathology
- 期: 卷 67, 编号 11 (2018)
- 页面: 2079-2087
- 栏目: Full Articles
- URL: https://journal-vniispk.ru/1066-5285/article/view/243186
- DOI: https://doi.org/10.1007/s11172-018-2332-z
- ID: 243186
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详细
The reaction of azoloannulated [1,2,4,5]tetrazines with guanidine was studied. New 3-guanidinoimidazo[1,2-b]- and 6-guanidino[1,2,4]triazolo[4,3-b] [1,2,4,5]tetrazines were synthesized using the nucleophilic substitution methodology. Compounds with high antibacterial and antiglycation activity were revealed.
作者简介
R. Ishmetova
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
编辑信件的主要联系方式.
Email: iri@ios.uran.ru
俄罗斯联邦, 22/20 ul. S. Kovalevskoi, Yekaterinburg, 620137
N. Ignatenko
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: iri@ios.uran.ru
俄罗斯联邦, 22/20 ul. S. Kovalevskoi, Yekaterinburg, 620137
A. Korotina
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: iri@ios.uran.ru
俄罗斯联邦, 22/20 ul. S. Kovalevskoi, Yekaterinburg, 620137
I. Ganebnykh
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: iri@ios.uran.ru
俄罗斯联邦, 22/20 ul. S. Kovalevskoi, Yekaterinburg, 620137
P. Slepukhin
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal University named after the first President of Russia B. N. Yeltsin
Email: iri@ios.uran.ru
俄罗斯联邦, 22/20 ul. S. Kovalevskoi, Yekaterinburg, 620137; 19 ul. Mira, Yekaterinburg, 620002
V. Babkova
Volgograd State Medical University, Ministry of Health of the Russian Federation
Email: iri@ios.uran.ru
俄罗斯联邦, 1 pl. Pavshikh Bortsov, Volgograd, 400131
N. Gerasimova
Ural Research Institute of Dermatovenereology and Immunopathology
Email: iri@ios.uran.ru
俄罗斯联邦, 8 ul. Shcherbakova, Yekaterinburg, 620076
N. Evstigneeva
Ural Research Institute of Dermatovenereology and Immunopathology
Email: iri@ios.uran.ru
俄罗斯联邦, 8 ul. Shcherbakova, Yekaterinburg, 620076
N. Zilberberg
Ural Research Institute of Dermatovenereology and Immunopathology
Email: iri@ios.uran.ru
俄罗斯联邦, 8 ul. Shcherbakova, Yekaterinburg, 620076
N. Kungurov
Ural Research Institute of Dermatovenereology and Immunopathology
Email: iri@ios.uran.ru
俄罗斯联邦, 8 ul. Shcherbakova, Yekaterinburg, 620076
G. Rusinov
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal University named after the first President of Russia B. N. Yeltsin
Email: iri@ios.uran.ru
俄罗斯联邦, 22/20 ul. S. Kovalevskoi, Yekaterinburg, 620137; 19 ul. Mira, Yekaterinburg, 620002
A. Spasov
Volgograd State Medical University, Ministry of Health of the Russian Federation
Email: iri@ios.uran.ru
俄罗斯联邦, 1 pl. Pavshikh Bortsov, Volgograd, 400131
O. Chupakhin
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal University named after the first President of Russia B. N. Yeltsin
Email: iri@ios.uran.ru
俄罗斯联邦, 22/20 ul. S. Kovalevskoi, Yekaterinburg, 620137; 19 ul. Mira, Yekaterinburg, 620002
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