Three-component green synthesis of 6-ethoxycarbonyl-5-methyl-7-(thien-2-yl)-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine, a promising antituberculosis drug
- 作者: Titova Y.A.1, Fedorova O.V.1, Rusinov G.L.1,2, Charushin V.N.1,2
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隶属关系:
- I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
- Ural Federal University named after the first President of Russia B. N. Yeltsin
- 期: 卷 68, 编号 12 (2019)
- 页面: 2271-2274
- 栏目: Full Articles
- URL: https://journal-vniispk.ru/1066-5285/article/view/243558
- DOI: https://doi.org/10.1007/s11172-019-2698-6
- ID: 243558
如何引用文章
详细
A new simple, technological, and environmentally friendly method for the catalyst-free synthesis in water of a promising antituberculosis drug, 6-ethoxycarbonyl-5-methyl-7-(thien-2-yl)-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine, was developed. The amount of the solvent in the reaction mixture has a decisive effect on the yield and purity of the target product.
作者简介
Yu. Titova
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
编辑信件的主要联系方式.
Email: titova@ios.uran.ru
俄罗斯联邦, 22 ul. S. Kovalevskoi, Yekaterinburg, 620990
O. Fedorova
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
Email: titova@ios.uran.ru
俄罗斯联邦, 22 ul. S. Kovalevskoi, Yekaterinburg, 620990
G. Rusinov
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal University named after the first President of Russia B. N. Yeltsin
Email: titova@ios.uran.ru
俄罗斯联邦, 22 ul. S. Kovalevskoi, Yekaterinburg, 620990; 19 ul. Mira, Yekaterinburg, 620002
V. Charushin
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal University named after the first President of Russia B. N. Yeltsin
Email: titova@ios.uran.ru
俄罗斯联邦, 22 ul. S. Kovalevskoi, Yekaterinburg, 620990; 19 ul. Mira, Yekaterinburg, 620002
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