Email this article Synthesis and Biological Evaluation of Amide Derivatives of Imidazopyridine as Anticancer Agents
- Authors: Ramesh V.1, Rao G.P.1, Ramachandran D.1, Chakravarthy A.K.2
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Affiliations:
- Department of Chemistry
- Integrated Product Development
- Issue: Vol 89, No 7 (2019)
- Pages: 1491-1495
- Section: Article
- URL: https://journal-vniispk.ru/1070-3632/article/view/222999
- DOI: https://doi.org/10.1134/S1070363219070193
- ID: 222999
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Abstract
A series of new amide derivatives of imidazopyridine is synthesized and structures of the products are confirmed by 1H and 13C NMR, and mass spectral data. The synthesized derivatives are screened for their anticancer activity against four human cancer cell lines: lung cancer (A549), breast cancer (MCF-7), melanoma cancer (A375), and colon cancer (HT-29). Six synthesized compounds exhibit more potent activity than the control drug.
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About the authors
V. Ramesh
Department of Chemistry
Author for correspondence.
Email: vramesh.chem1@gmail.com
India, Guntur, Andhra Pradesh
G. Purna Chander Rao
Department of Chemistry
Email: vramesh.chem1@gmail.com
India, Guntur, Andhra Pradesh
D. Ramachandran
Department of Chemistry
Email: vramesh.chem1@gmail.com
India, Guntur, Andhra Pradesh
A. Kalyan Chakravarthy
Integrated Product Development
Email: vramesh.chem1@gmail.com
India, Bachupally, Hyderabad
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