Antimicrobial Activity of Some New N-Glycosylidene Carbohydrazide Derivatives


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New N-glycosyl carbohydrazide derivatives and their annulated C-nucleosides have been synthesized via reaction of N-[4-(hydrazinecarbonyl)phenyl]-8-hydroxy-7-iodoquinoline-5-sulfonamide with different aldoses and characterized by spectroscopic and elemental analyses. Some selected compounds have been screened for activity and 4d showed maximum antimicrobial activity comparable to that of standard drugs.

作者简介

N. Khalifa

Department of Pharmaceutical Chemistry, Drug Exploration and Development Chair (DEDC), College of Pharmacy; Department of Therapeutical Chemistry, Pharmaceutical and Drug Industries Division

编辑信件的主要联系方式.
Email: nagykhalifa@hotmail.com
沙特阿拉伯, Riyadh, 11451; Dokki, Cairo, 12622

M. Al-Omar

Department of Pharmaceutical Chemistry, Drug Exploration and Development Chair (DEDC), College of Pharmacy

Email: nagykhalifa@hotmail.com
沙特阿拉伯, Riyadh, 11451

E. Nossier

Department of Pharmaceutical Chemistry, Faculty of Pharmacy (Girls)

Email: nagykhalifa@hotmail.com
埃及, Cairo

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