Email this article Antimicrobial Activity of Some New N-Glycosylidene Carbohydrazide Derivatives
- Authors: Khalifa N.M.1,2, Al-Omar M.A.1, Nossier E.S.3
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Affiliations:
- Department of Pharmaceutical Chemistry, Drug Exploration and Development Chair (DEDC), College of Pharmacy
- Department of Therapeutical Chemistry, Pharmaceutical and Drug Industries Division
- Department of Pharmaceutical Chemistry, Faculty of Pharmacy (Girls)
- Issue: Vol 87, No 12 (2017)
- Pages: 2909-2914
- Section: Letters to the Editor
- URL: https://journal-vniispk.ru/1070-3632/article/view/221746
- DOI: https://doi.org/10.1134/S1070363217120301
- ID: 221746
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Abstract
New N-glycosyl carbohydrazide derivatives and their annulated C-nucleosides have been synthesized via reaction of N-[4-(hydrazinecarbonyl)phenyl]-8-hydroxy-7-iodoquinoline-5-sulfonamide with different aldoses and characterized by spectroscopic and elemental analyses. Some selected compounds have been screened for activity and 4d showed maximum antimicrobial activity comparable to that of standard drugs.
About the authors
N. M. Khalifa
Department of Pharmaceutical Chemistry, Drug Exploration and Development Chair (DEDC), College of Pharmacy; Department of Therapeutical Chemistry, Pharmaceutical and Drug Industries Division
Author for correspondence.
Email: nagykhalifa@hotmail.com
Saudi Arabia, Riyadh, 11451; Dokki, Cairo, 12622
M. A. Al-Omar
Department of Pharmaceutical Chemistry, Drug Exploration and Development Chair (DEDC), College of Pharmacy
Email: nagykhalifa@hotmail.com
Saudi Arabia, Riyadh, 11451
E. S. Nossier
Department of Pharmaceutical Chemistry, Faculty of Pharmacy (Girls)
Email: nagykhalifa@hotmail.com
Egypt, Cairo
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