Synthesis of 2-Substituted 6-(Polyfluoromethyl)pyrimidine-4-carbaldehyde Acetals
- Autores: Belyaev D.V.1, Chizhov D.L.1, Rusinov G.L.1,2, Charushin V.N.1,2
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Afiliações:
- Postovskii Institute of Organic Synthesis, Ural Branch
- Yeltsin Ural Federal University
- Edição: Volume 55, Nº 6 (2019)
- Páginas: 879-882
- Seção: Short Communications
- URL: https://journal-vniispk.ru/1070-4280/article/view/220794
- DOI: https://doi.org/10.1134/S1070428019060204
- ID: 220794
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Resumo
Heterocyclization of 5,5-difluoro- and 5,5,5-trifluoro-2,4-dioxopentanal dimethyl acetals with amidines in the presence of 4 equiv of triethyl borate afforded 2-substituted 6-(difluoromethyl)- and 6-(trifluoromethyl)pyrimidine-4-carbaldehyde dimethyl acetals in high yields.
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Sobre autores
D. Belyaev
Postovskii Institute of Organic Synthesis, Ural Branch
Email: dlchizhov@ios.uran.ru
Rússia, Yekaterinburg
D. Chizhov
Postovskii Institute of Organic Synthesis, Ural Branch
Autor responsável pela correspondência
Email: dlchizhov@ios.uran.ru
Rússia, Yekaterinburg
G. Rusinov
Postovskii Institute of Organic Synthesis, Ural Branch; Yeltsin Ural Federal University
Email: dlchizhov@ios.uran.ru
Rússia, Yekaterinburg; Yekaterinburg
V. Charushin
Postovskii Institute of Organic Synthesis, Ural Branch; Yeltsin Ural Federal University
Email: dlchizhov@ios.uran.ru
Rússia, Yekaterinburg; Yekaterinburg
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