Study of the absorbent properties of alginic acid
- Authors: Zakharov А.S.1, Barishnikova M.I.1, Saf’yanov M.A.1, Vasilovsky I.N.1, Korotkova N.V.1, Sukhova А.А.1, Fomina D.I.1, Ivankina I.V.1
-
Affiliations:
- Ryazan State Medical University
- Issue: Vol 28, No 6 (2025)
- Pages: 14-20
- Section: Biological chemistry
- URL: https://journal-vniispk.ru/1560-9596/article/view/310590
- DOI: https://doi.org/10.29296/25877313-2025-06-02
- ID: 310590
Cite item
Open Access
Access granted
Subscription Access
Abstract
Introduction.Alginicacidis a naturalheteropolysaccharide of brownalgae,consistingofresidues of mannuronicandguluronicacids.It is usedinvariousfields:medicine,foodandpharmaceuticalindustry,cosmetology,ecology,etc. Itsability to bindandretainwatertoformhydrogels is usedin the development of newtechnologiesandmaterials. The structure of thiscompoundisinterestingfrom the point of view of studyingitsabsorbentpropertiesinrelationtosubstances of variouscompositionandstructure.
Material and methods.thestudypresentsvariousmethods for determiningsolutionconcentrationsbasedonphotocolorimetricandspectrophotometricanalysis.Thefollowing compounds wereselectedasexperimentalcompoundsfor the study of absorbentactivity: anions–nitrite,sulfate,iodide;metalcations–calciumandiron(III);protein–glutathione;organicdyes–methyleneblueandmethylorange.
Results.during the study, it turned out thatalginicacidcanabsorb the followingcompounds:nitriteanions-by90.4%,sulfateanions–by71.8%,iodideanions–by28.34%,calciumcations–by58.06%,iron(III)cations–by75.41%,protein–by48.33%,methyleneblue–by 84.22%andmethylorange–by83.72%. The authorssuggestthat the specificabsorbingactivity of alginicacidcan be explained by the followingproperties: alginicacidbindsmetalionsdue to the content of carboxylgroupsand a change in the gelstructureduringswelling; absorption of proteins is caused by electrostaticinteractionwithalginicacidandcompetitionwithmetalcationsforbindingtocarboxylgroups;absorption of anionscanbeassociatedwithelectrostaticinteractionwithcarboxylgroups.
Conclusions. alginic acid has a pronounced absorbent ability in relation to a wide range of compounds of various chemical nature. This feature makes alginic acid a compound suitable for use in filtration and dialysis systems for various purposes, including medical ones.
Keywords
Full Text
##article.viewOnOriginalSite##About the authors
А. S. Zakharov
Ryazan State Medical University
Author for correspondence.
Email: AlexanderZakharov2019@yandex.ru
ORCID iD: 0000-0002-4004-7474
SPIN-code: 4906-9088
Assistant of the Department of Biological Chemistry
Russian Federation, Visokovoltnaya str., 9, Ryazan, 390026M. I. Barishnikova
Ryazan State Medical University
Email: masha.bari04@gmail.com
ORCID iD: 0009-0004-0407-6536
Student of the Faculty of General Medicine
Russian Federation, Visokovoltnaya str., 9, Ryazan, 390026M. A. Saf’yanov
Ryazan State Medical University
Email: bellkoks@yandex.ru
ORCID iD: 0009-0008-3895-0171
Student of the Faculty of General Medicine
Russian Federation, Visokovoltnaya str., 9, Ryazan, 390026I. N. Vasilovsky
Ryazan State Medical University
Email: vania_vania_2018@list.ru
ORCID iD: 0009-0005-0294-4990
Student of the Faculty of General Medicine
Russian Federation, Visokovoltnaya str., 9, Ryazan, 390026N. V. Korotkova
Ryazan State Medical University
Email: fnv8@yandex.ru
ORCID iD: 0000-0001-7974-2450
SPIN-code: 3651-3813
Ph.D. (Med.), Associate Professor, Docent of the Department of Biological Chemistry
Russian Federation, Visokovoltnaya str., 9, Ryazan, 390026А. А. Sukhova
Ryazan State Medical University
Email: rrraaa724@gmail.com
ORCID iD: 0009-0006-5482-6969
Resident
Russian Federation, Visokovoltnaya str., 9, Ryazan, 390026D. I. Fomina
Ryazan State Medical University
Email: fnv8@yandex.ru
ORCID iD: 0009-0008-5532-6303
Student of the Faculty of General Medicine
Russian Federation, Visokovoltnaya str., 9, Ryazan, 390026I. V. Ivankina
Ryazan State Medical University
Email: ira.ivankina.02@mail.ru
ORCID iD: 0009-0000-6789-8853
Student of the Faculty of General Medicine
Russian Federation, Visokovoltnaya str., 9, Ryazan, 390026References
- Ryabova M.N., Seleznev A.V., I.A. Fokin i dr. Primenenie mannitol termostabilizirovanny`x GK-kompleksov v lechenii gonartroza. Nauka molody`x (Eruditio Juvenium). 2022; 10(3): 277–288. (In Russ.). doi: 10.23888/HMJ2022103277-288.
- Lipatov V.A., Fronchek E`.V., Grigor`yan A.Yu. i dr. Ocenka e`ffektivnosti novy`x obrazczov mestny`x krovoostanavlivayushhix sredstv na osnove xitozana posle rezekcii pecheni v e`ksperimente. Rossijskij mediko-biologicheskij vestnik im. akademika I.P. Pavlova. 2023; 31(1): 89–96. (In Russ.). doi: 10.17816/PAVLOVJ108094.
- Podkorytova A.V., Roshhina A.N. Morskie burye vodorosli – perspektivnyj istochnik BAV dlja medicinskogo, farmacevticheskogo i pishhevogo primenenija. Trudy VNIRO. 2021; 186(4): 156–172. (In Russ.). doi: 10.36038/2307-3497-2020-181-235-256.
- Zaharova V.A., Fidorovskaja Ju., Hlystova T.S. I dr. Proizvodnye al'ginovoj kisloty: osobennosti stroenija, svojstva i perspektivy ispol'zovanija v medicine. Industrial Processes and Technologies. 2022; 2(5): 64–79. (In Russ.). doi: 10.37816/2713-0789-2022-2-5(7)-64-79.
- Kuznecova T.A., Besednova N.N., Usov V.V. i dr. Biosovmestimye i biodegradiruemye ranevye pokrytija na osnove polisaharidov iz morskih vodoroslej (obzor literatury). Vestnik hirurgii imeni II Grekova. 2020; 179(4): 109–115. (In Russ.). doi: 10.24884/0042-4625-2020-179-4-109-115.
- Kalis E.J.J., Davis T.A., Town R.M. et al. Impact of pH on CdII partitioning between alginate gel and aqueous media. Environmental Chemistry. 2009; 6(4): 305–310. doi: 10.1071/EN09060.
- Zhang Y., Zhao K., Yang Z. et al. Calcium alginate and barium alginate hydrogel filtration membrane coated on fibers for molecule/ion separation. Separation and Purification Technology. 2021; 270: 118761. doi: 10.1016/j.seppur.2021.118761.
- Zhao K., Zhang X., Wei J. et al. Calcium alginate hydrogel filtration membrane with excellent anti-fouling property and controlled separation performance. Journal of Membrane Science. 2015; 492: 536–546. doi: 10.1016/j.memsci.2015.05.075.
- Abka-Khajouei R., Tounsi L., Shahabi N. et al. Structures, Properties and Applications of Alginates. Marine Drugs. 2022; 20(6): 364. doi: 10.3390/md20060364.
- Rinaudo M. On the abnormal exponents aν and aD in Mark Houwink type equations for wormlike chain polysaccharides. Polymer Bulletin. 1992; 27: 585–589. doi: 10.1007/BF00300608.
- Giridhar Reddy S. Alginates – A Seaweed Product: Its Properties and Applications. Properties and Applications of Alginates. 2021. doi: 10.5772/intechopen.98831.
- Golmohamadi M., Wilkinson K.J. Diffusion of ions in a calcium alginate hydrogel-structure is the primary factor controlling diffusion. Carbohydrate polmers. 2013; 94(1): 82–87. doi: 10.1016/j.carbpol.2013.01.046.
- Zhao L., Wang J., Zhang P. et al. Absorption of Heavy Metal Ions by Alginate. Bioactive Seaweeds for Food Applications. Bioactive Seaweeds for Food Applications. 2018: 255–268. doi: 10.1016/B978-0-12-813312-5.00013-3.
- Gao N., Xie W., Xu L. et al. Characterization of a chlorine resistant and hydrophilic TiO2/calcium alginate hydrogel filtration membrane used for protein purification maintaining protein structure. International Journal of Biological Macromolecules. 2023; 253(6): 126367. doi: 10.1016/j.ijbiomac.2023.126367.
- Zhao D., Shen Z., Shen X. Dual-functional calcium alginate hydrogel beads for disinfection control and removal of dyes in water. 2021; 188: 253–262. doi: 10.1016/j.ijbiomac.2021.07.177.
Supplementary files
