The biodegradation of fullerene C60 by myeloperoxidase


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Abstract

It is shown for the first time that the mammalian enzymes can cause the degradation of the C60 fullerene molecules. This biodegradation is caused by the action of а hypochlorite generated neutrophil enzyme myeloperoxidase of fullerene molecule and leads to the loss of the topology of the fullerene core.

About the authors

E. V. Litasova

Institute of Experimental Medicine

Author for correspondence.
Email: llitasova@mail.ru
Russian Federation, ul. Akademika Pavlova 12, St. Petersburg, 197376

V. V. Iljin

Institute of Experimental Medicine

Email: llitasova@mail.ru
Russian Federation, ul. Akademika Pavlova 12, St. Petersburg, 197376

A. V. Sokolov

Institute of Experimental Medicine; St. Petersburg State University

Email: llitasova@mail.ru
Russian Federation, ul. Akademika Pavlova 12, St. Petersburg, 197376; Universitetskaya nab. 7/9, St. Petersburg, 199034

V. B. Vasilyev

Institute of Experimental Medicine; St. Petersburg State University

Email: llitasova@mail.ru
Russian Federation, ul. Akademika Pavlova 12, St. Petersburg, 197376; Universitetskaya nab. 7/9, St. Petersburg, 199034

M. A. Dumpis

Institute of Experimental Medicine

Email: llitasova@mail.ru
Russian Federation, ul. Akademika Pavlova 12, St. Petersburg, 197376

L. B. Piotrovskiy

Institute of Experimental Medicine

Email: llitasova@mail.ru
Russian Federation, ul. Akademika Pavlova 12, St. Petersburg, 197376

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