The biodegradation of fullerene C60 by myeloperoxidase
- Authors: Litasova E.V.1, Iljin V.V.1, Sokolov A.V.1,2, Vasilyev V.B.1,2, Dumpis M.A.1, Piotrovskiy L.B.1
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Affiliations:
- Institute of Experimental Medicine
- St. Petersburg State University
- Issue: Vol 471, No 1 (2016)
- Pages: 417-420
- Section: Biochemistry, Biophysics, and Molecular Biology
- URL: https://journal-vniispk.ru/1607-6729/article/view/211746
- DOI: https://doi.org/10.1134/S1607672916060119
- ID: 211746
Cite item
Abstract
It is shown for the first time that the mammalian enzymes can cause the degradation of the C60 fullerene molecules. This biodegradation is caused by the action of а hypochlorite generated neutrophil enzyme myeloperoxidase of fullerene molecule and leads to the loss of the topology of the fullerene core.
About the authors
E. V. Litasova
Institute of Experimental Medicine
Author for correspondence.
Email: llitasova@mail.ru
Russian Federation, ul. Akademika Pavlova 12, St. Petersburg, 197376
V. V. Iljin
Institute of Experimental Medicine
Email: llitasova@mail.ru
Russian Federation, ul. Akademika Pavlova 12, St. Petersburg, 197376
A. V. Sokolov
Institute of Experimental Medicine; St. Petersburg State University
Email: llitasova@mail.ru
Russian Federation, ul. Akademika Pavlova 12, St. Petersburg, 197376; Universitetskaya nab. 7/9, St. Petersburg, 199034
V. B. Vasilyev
Institute of Experimental Medicine; St. Petersburg State University
Email: llitasova@mail.ru
Russian Federation, ul. Akademika Pavlova 12, St. Petersburg, 197376; Universitetskaya nab. 7/9, St. Petersburg, 199034
M. A. Dumpis
Institute of Experimental Medicine
Email: llitasova@mail.ru
Russian Federation, ul. Akademika Pavlova 12, St. Petersburg, 197376
L. B. Piotrovskiy
Institute of Experimental Medicine
Email: llitasova@mail.ru
Russian Federation, ul. Akademika Pavlova 12, St. Petersburg, 197376
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