Email this article Stability of Chromatin Remodeling Complex Subunits Is Determined by Their Phosphorylation Status
- Authors: Azieva A.M.1,2, Sheinov A.A.1, Galkin F.A.1, Georgieva S.G.3, Soshnikova N.V.1
-
Affiliations:
- Institute of Gene Biology
- Kurchatov Institute National Research Center
- Engelhardt Institute of Molecular Biology
- Issue: Vol 479, No 1 (2018)
- Pages: 66-68
- Section: Biochemistry, Biophysics, and Molecular Biology
- URL: https://journal-vniispk.ru/1607-6729/article/view/212140
- DOI: https://doi.org/10.1134/S1607672918020035
- ID: 212140
Cite item
Open Access
Access granted
Subscription Access
Abstract
It was found that, in the differentiated cells of mouse brain, the level of core (Brg1 and BAF155) and specific (BRD7, BAF180, and PHF10) subunits of the chromatin-remodeling complex PBAF is reduced compared to the undifferentiated proliferating cells. Phosphorylation of PBAF complex subunits is required for maintaining their stability in differentiated brain cells.
About the authors
A. M. Azieva
Institute of Gene Biology; Kurchatov Institute National Research Center
Email: so2615nat@gmail.com
Russian Federation, Moscow, 119334; Moscow, 123182
A. A. Sheinov
Institute of Gene Biology
Email: so2615nat@gmail.com
Russian Federation, Moscow, 119334
F. A. Galkin
Institute of Gene Biology
Email: so2615nat@gmail.com
Russian Federation, Moscow, 119334
S. G. Georgieva
Engelhardt Institute of Molecular Biology
Email: so2615nat@gmail.com
Russian Federation, Moscow
N. V. Soshnikova
Institute of Gene Biology
Author for correspondence.
Email: so2615nat@gmail.com
Russian Federation, Moscow, 119334
Supplementary files
