Synthesis of Proteins Encoded by the Early Genes E2, E6, and E7 of Papillomavirus of Type 16 in the Plant Expression System


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Abstract

An expression system for the synthesis of early antigenic proteins HPV16 E2, HPV16 E6, and HPV16 E7 of high-risk papillomavirus based on transgenic tomato fruits was developed. It is planned to use the early antigenic proteins synthesized to create a therapeutic vaccine against cervical cancer.

About the authors

R. K. Salyaev

Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch; Irkutsk Scientific Center, Siberian Branch

Author for correspondence.
Email: salyaev@sifibr.irk.ru
Russian Federation, Irkutsk, 664033; Irkutsk, 664033

N. I. Rekoslavskaya

Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch; Irkutsk Scientific Center, Siberian Branch

Email: salyaev@sifibr.irk.ru
Russian Federation, Irkutsk, 664033; Irkutsk, 664033

A. S. Stolbikov

Siberian Institute of Plant Physiology and Biochemistry, Siberian Branch; Irkutsk Scientific Center, Siberian Branch

Email: salyaev@sifibr.irk.ru
Russian Federation, Irkutsk, 664033; Irkutsk, 664033

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