Email this article Biotechnological Method of Preparation and Characterization of Recombinant Antimicrobial Peptide Avicin A from Enterococcus avium
- Authors: Balandin S.V.1, Finkina E.I.1, Nurmukhamedova E.K.1, Tagaev A.A.1, Umnyakova E.S.2, Kokryakov V.N.2, Shvets V.I.3, Ovchinnikova T.V.1
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Affiliations:
- Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
- Institute of Experimental Medicine, Almazov National Medical Research Center
- Lomonosov Institute of Fine Chemical Technology, Russian Technological University (MIREA)
- Issue: Vol 484, No 1 (2019)
- Pages: 42-44
- Section: Biochemistry, Biophysics, and Molecular Biology
- URL: https://journal-vniispk.ru/1607-6729/article/view/212720
- DOI: https://doi.org/10.1134/S1607672919010113
- ID: 212720
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Abstract
Avicin A is a bacteriocin from the gram-positive bacterium Enterococcus avium. It exhibits a high microbicidal activity against bacteria of the genus Listeria, a causative agent of the severe human infection listeriosis. We developed a biotechnological method for obtaining avicin A and characterized its structure and biological activity. We also proposed a possible mechanism of the antimicrobial action of avicin A.
About the authors
S. V. Balandin
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Author for correspondence.
Email: arenicin@mail.ru
Russian Federation, Moscow, 117997
E. I. Finkina
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: arenicin@mail.ru
Russian Federation, Moscow, 117997
E. K.-A. Nurmukhamedova
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: arenicin@mail.ru
Russian Federation, Moscow, 117997
A. A. Tagaev
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: arenicin@mail.ru
Russian Federation, Moscow, 117997
E. S. Umnyakova
Institute of Experimental Medicine, Almazov National Medical Research Center
Email: arenicin@mail.ru
Russian Federation, St. Petersburg, 197341
V. N. Kokryakov
Institute of Experimental Medicine, Almazov National Medical Research Center
Email: arenicin@mail.ru
Russian Federation, St. Petersburg, 197341
V. I. Shvets
Lomonosov Institute of Fine Chemical Technology, Russian Technological University (MIREA)
Email: arenicin@mail.ru
Russian Federation, Moscow, 117571
T. V. Ovchinnikova
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: arenicin@mail.ru
Russian Federation, Moscow, 117997
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