电邮这篇文章 Comparative analysis of bone grafting materials for jaw defect reconstruction
- 作者: Samburova K.M.1, Amkhadova M.A.1, Mikaya M.Z.1
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隶属关系:
- Moscow Regional Research and Clinical Institute
- 期: 卷 29, 编号 4 (2025)
- 页面: 334-339
- 栏目: Original Study Articles
- URL: https://journal-vniispk.ru/1728-2802/article/view/313613
- DOI: https://doi.org/10.17816/dent685616
- EDN: https://elibrary.ru/ZEELRT
- ID: 313613
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详细
BACKGROUND: Autogenous bone remains the gold standard for grafting because of its osteogenic properties; however, its use is limited. Allogeneic and xenogeneic grafts are more convenient but require meticulous preparation. Combined approaches, including the use of growth factors, represent a promising direction. Optimal material selection should be tailored to individual patient factors and the clinical context. The article compares Russian-manufactured bone grafting materials with imported counterparts and reports a histological examination of the newly formed bone tissue.
AIM: To analyze newly formed bone tissue in patients following the use of contemporary bone graft materials.
METHODS: A total of 79 bone-augmentation procedures were performed using xenogeneic materials—both imported and Russian-manufactured grafts; 39 of these cases were selected for histological assessment of the newly formed bone. Patients were allocated into 3 groups according to the bone-graft combinations placed at implantation: group 1, Osteomatrix, Bioimplant GAP, and Biomatrix (Konektbiopharm, Russia); group 2, Bio-Oss and Bio-Gide (Geistlich Pharma AG, Switzerland); and group 3, bioOST and bioPLATE (Cardioplant, Russia). Biopsy specimens of newly formed bone were obtained 5 months postoperatively for subsequent histological assessment of tissue and cellular architecture.
RESULTS: Group 1 demonstrated predominance of mature lamellar bone with active osteoblasts and preosteoblasts. Application of the group 2 and group 3 grafts yielded high bone density and active osteogenesis, with trabecular bone formation.
CONCLUSION: Clinical, radiographic, and histological data suggest that Osteomatrix, Bioimplant GAP, Biomatrix, bioOST, and bioPLATE grafting materials support uniform bone regeneration. Their regenerative potential is comparable to that of imported counterparts, indicating their viability as alternative grafting materials.
作者简介
Kristina Samburova
Moscow Regional Research and Clinical Institute
编辑信件的主要联系方式.
Email: samburova-cristina@yandex.ru
ORCID iD: 0009-0002-7621-2811
俄罗斯联邦, 61/2 Shchepkina st, Moscow, 129110
Malkan Amkhadova
Moscow Regional Research and Clinical Institute
Email: amkhadova@mail.ru
ORCID iD: 0000-0002-9105-0796
SPIN 代码: 3018-7883
MD, Dr. Sci. (Medicine), Professor
俄罗斯联邦, 61/2 Shchepkina st, Moscow, 129110Mariam Mikaya
Moscow Regional Research and Clinical Institute
Email: mmikaa61@gmail.com
ORCID iD: 0009-0000-4361-3542
俄罗斯联邦, 61/2 Shchepkina st, Moscow, 129110
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