Features of the course of relapsing polychondritis (clinical case)

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Abstract

Relapsing polychondritis is a rare disease of autoimmune nature. At this stage, the problems of understanding the pathophysiology of relapsing polychondritis, its diagnosis, assessment of activity and prognosis, as well as treatment have not been resolved. The disease develops through exacerbation of remissions. It is characterized by clinical poly-morphism, requiring a team approach from specialists from different specialties. Manifestations usually occur gradually over time, and their frequency depends on the duration, activity and severity of the disease. Clinical heterogeneity of the disease is a source of diagnostic errors. The differential diagnosis in most cases concerns the involvement of each organ, which may appear immediately in a particular patient, but in most cases appears gradually, with an average of two symptoms at the onset of the disease. Purpose of the study: analysis of a clinical case of relapsing polychondritis, the clinical picture, the need for early diagnosis and the prescription of pathogenetic therapy. The article discusses our own clinical observation of relapsing polychondritis identified in a 62-year-old patient. A differential di-agnosis was made between the patient’s disease, systemic scleroderma and necrotizing vasculitis. 

About the authors

Olga G. Radaykina

Ogarev Mordovia State University

Email: mrsolga5@yandex.ru

Candidate of medical sciences, associate professor, associate professor of the sub-department of faculty therapy with a course in medical rehabilitation, Medical Institute

(68 Bolshevistskaya street, Saransk, Russia)

Anna A. Usanova

Ogarev Mordovia State University

Email: anna61-u@mail.ru

Doctor of medical sciences, professor, head of the sub-department of faculty therapy with a course in medical rehabilitation, Medical Institute

(68 Bolshevistskaya street, Saransk, Russia)

Irina Kh. Fazlova

Ogarev Mordovia State University

Email: fazlova@inbox.ru

Candidate of medical sciences, associate professor, associate professor of the sub-department of faculty therapy with a course of medical rehabilitation, Medical Institute

(68 Bolshevistskaya street, Saransk, Russia)

Natalya N. Guranova

Ogarev Mordovia State University

Email: nguranova@mail.ru

Candidate of medical sciences, associate professor, associate professor of the sub-department of faculty therapy with a course of medical rehabilitation, Medical Institute

(68 Bolshevistskaya street, Saransk, Russia)

Ekaterina V. Veshkina

Ogarev Mordovia State University

Author for correspondence.
Email: ekaterinaveshkina@inbox.ru

Resident of the sub-department of outpatient and polyclinic therapy, Medical Institute

(68 Bolshevistskaya street, Saransk, Russia)

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