Email this article Influence of complex therapy on amino acid composition of blood in calves with gastrointestinal tract diseases
- Authors: Pudovkin N.A.1, Apieva E.Z.2, Smutnev P.V.1
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Affiliations:
- Saratov State University of Genetics, Biotechnology and Engineering named after N.I. Vavilov
- Penza State Agrarian University
- Issue: Vol 20, No 2 (2025): Applied aspects of pharmaceutical science in veterinary medicine
- Pages: 227-238
- Section: Applied aspects of pharmaceutical science in veterinary medicine
- URL: https://journal-vniispk.ru/2312-797X/article/view/315844
- DOI: https://doi.org/10.22363/2312-797X-2025-20-2-227-238
- EDN: https://elibrary.ru/MYLXIW
- ID: 315844
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Abstract
Significant changes in the amino acid composition of the blood were found in calves with dyspepsia. Amino acid analysis showed a heavy decrease in the levels of specific non-essential and essential amino acids in calves with dyspepsia. The aim of the study was to evaluate the effect of fermented colostrum on the amino acid composition of blood during the treatment of calves with dyspepsia. Three groups of 10 day-old calves were formed for the study. The first group of animals (the control group) was fed regular colostrum without fermentation for 7 days. The second and third groups (experimental) were calves with diarrhea syndrome. The second group of calves was administered 2 ml of Flunex intramuscularly, Roncoleukin 1500 IU/kg intravenously, and Thymogen was administered to calves intramuscularly at a dose of 100 mcg per animal on the 1st and 20th days of life. A full dose of milk was given in the evening milk feeding. The third group of calves underwent the same drug therapy. But in the morning and evening milk feedings they were given a full dose of colostrum fermented by Productiv Acid SE. The use of Flunex, Roncoleukin, Thymogen for the treatment of the disease does not contribute to the full restoration of the amino acid composition of the blood. After treatment, the content of specific essential amino acids did not reach the levels of healthy animals. The total amount of amino acids was also below the control values. Adding fermented colostrum to the diet of calves that were undergoing treatment contributes to the restoration of the amino acid composition of the blood. The content of specific essential amino acids slightly differed from the control values in this group animals. The amount of non-essential amino acids increased significantly and almost reached the control values.
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About the authors
Nikolaj A. Pudovkin
Saratov State University of Genetics, Biotechnology and Engineering named after N.I. Vavilov
Email: niko-pudovkin@yandex.ru
ORCID iD: 0000-0003-0665-1130
SPIN-code: 7309-1025
Doctor of Biological Sciences, Professor, Head of the Department of Morphology, Animal Pathology and Biology
4 Pyotr Stolypin Avenue, bldg. 3, Saratov, 410012, Russian FederationEl’za Zh. Apieva
Penza State Agrarian University
Email: elsa-apieva@yandex.ru
ORCID iD: 0000-0002-5422-5737
SPIN-code: 4930-8626
Associate Professor of the Department of Veterinary Medicine
30 Botanicheskaya Street, Penza, 440014, Russian FederationPetr V. Smutnev
Saratov State University of Genetics, Biotechnology and Engineering named after N.I. Vavilov
Author for correspondence.
Email: smutnev-asd@yandex.ru
ORCID iD: 0000-0001-8393-9336
SPIN-code: 9541-6618
Candidate of Veterinary Sciences, Associate Professor of the Department of Microbiology and Biotechnology
4 Pyotr Stolypin Avenue, bldg. 3, Saratov, 410012, Russian FederationReferences
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