Risk factors for premature placental abruption: a retrospective observational comparative study
- Authors: Rudakova I.S.1,2, Shifman E.M.3, Tikhova G.P.1
-
Affiliations:
- Petrozavodsk State University
- Republican Perinatal Center
- Moscow Regional Research Clinical Institute named after M.F. Vladimirsky
- Issue: Vol 9, No 3 (2022)
- Pages: 153-161
- Section: Original study articles
- URL: https://journal-vniispk.ru/2313-8726/article/view/111030
- DOI: https://doi.org/10.17816/2313-8726-2022-9-3-153-161
- ID: 111030
Cite item
Full Text
Abstract
AIM: This study aimed to determine the risk factors for premature placental abruption (PPA).
MATERIALS AND METHODS: A retrospective comparative study was conducted at the Republican Perinatal Center of Petrozavodsk. The study group included 106 patients with a confirmed diagnosis of PPA from 2007 to 2017. The control group (comparison) included 106 women without PPA and abnormal placenta.
RESULTS: The statistical data analysis revealed the following risk factors of PPA: lack of higher education in the patient (odds ratio [OR]: 0.51, 95% confidence interval [CI]: 0.28–0.90); smoking (OR: 3.41, 95% CI: 1.29–8.97); chronic liver disease (OR: 7.29, 95% CI: 1.60–33.06); uterine abnormalities (OR: 8.57, 95% CI: 1.05–69.79); and pelvic inflammatory disease (OR: 6.12, 95% CI: 2.56–14.62). The effect of chronic hypertension, chronic kidney disease, and anemia on the occurrence of PPA in our study was not significant.
CONCLUSION: An increased risk of PPA was found in patients who smoke without higher education with chronic liver disease, uterine abnormalities, and pelvic inflammatory diseases.
Keywords
Full Text
##article.viewOnOriginalSite##About the authors
Irina S. Rudakova
Petrozavodsk State University; Republican Perinatal Center
Author for correspondence.
Email: irinarudakova21@gmail.com
ORCID iD: 0000-0003-2131-487X
Postgraduate Student, Obstetrician-Gynecologist
Russian Federation, Petrozavodsk; 9, Syktyvkarskaya str., Petrozavodsk, 185002Efim M. Shifman
Moscow Regional Research Clinical Institute named after M.F. Vladimirsky
Email: eshifman@mail.ru
ORCID iD: 0000-0002-6113-8498
MD, Dr. Sci. (Med.), Рrofessor
Russian Federation, MoscowGalina P. Tikhova
Petrozavodsk State University
Email: tikhovag@gmail.ru
ORCID iD: 0000-0003-1128-9666
research associate
Russian Federation, PetrozavodskReferences
- Tikkanen M. Placental abruption: epidemiology, risk factors and consequences. Acta Obstet Gynecol Scand. 2011;90(2):140–149. doi: 10.1111/j.1600-0412.2010.01030.x
- Downes KL, Grantz KL, Shenassa ED. Maternal, labor, delivery, and perinatal outcomes associated with placental abruption: a systematic review. Am J Perinatol. 2017;34(10):935–957. doi: 10.1055/s-0037-1599149
- Waters JH, Bonnet MP. When and how should I transfuse during obstetric hemorrhage? Int J Obstet Anesth. 2021;46:102973. doi: 10.1016/j.ijoa.2021.102973
- Hasegawa J, Katsuragi S, Tanaka H, et al. Decline in maternal death due to obstetric haemorrhage between 2010 and 2017 in Japan. Scientific Reports. 2019;9(1):1–7. doi: 10.1038/s41598-019-47378-z
- Schmidt P, Skelly CL, Raines DA. Placental abruption (abruptio placentae). Treasure Island, FL : StatPearls Publishing; 2022.
- Ananth CV, Jablonski K, Myatt L, et al. Risk of ischemic placental disease in relation to family history of preeclampsia. Am J Perinatol. 2019;36(6):624–631. doi: 10.1055/s-0038-1672177
- Johnson KM, Smith L, Modest AM, et al. Angiogenic factors and prediction for ischemic placental disease in future pregnancies. Pregnancy Hypertens. 2021;25:12–17. doi: 10.1016/j.preghy.2021.05.011
- Ni S, Wang X, Cheng X. The comparison of placental abruption coupled with and without preeclampsia and/or intrauterine growth restriction in singleton pregnancies. J Matern Fetal Neonatal Med. 2021;34(9):1395–1400. doi: 10.1080/14767058.2019.1637850
- Tikkanen M, Riihimäki O, Gissler M, et al. Decreasing incidence of placental abruption in Finland during 1980–2005. Acta Obstet Gynecol Scand. 2012;91(9):1046–1052. doi: 10.1111/j.1600-0412.2012.01457.x
- Downes KL, Shenassa ED, Grantz KL. Neonatal Outcomes Associated with Placental Abruption. Am J Epidemiol. 2017;186(12):1319–1328. doi: 10.1093/aje/kwx202
- Heitkamp A, Meulenbroek A, van Roosmalen J, et al. Maternal mortality: near-miss events in middle-income countries, a systematic review. Bull World Health Organ. 2021;99(10):693. doi: 10.2471/BLT.21.285945
- Bezhenar VF, Filippov OS, Adamyan LV, Nesterov IM. Monitoring in obstetric critical care (“maternal near miss”) in the Northwestern Federal District of the Russian Federation in 2018–2019. Journal of Obstetrics and Women’s Diseases. 2021;70(1):5–18. (in Russ). doi: 10.17816/JOWD64123
- Martinelli KG, Garcia ÉM, Santos Neto ETD, Gama SGND. Advanced maternal age and its association with placenta praevia and placental abruption: a meta-analysis. Cad Saude Publica. 2018;34(2):e00206116. doi: 10.1590/0102-311X00206116
- Guo GL, Zhang YK, Li YL, et al. Epidemiological characteristics and related risk factors on placental abruption in Hebei Province. Zhonghua Liu Xing Bing Xue Za Zhi. 2018;39(12):1621–1625. doi: 10.3760/cma.j.issn.0254-6450.2018.12.016
- Huang K, Yan J, Li X, et al. A risk factor analysis and prediction model of placental abruption. Int J Clin Experim Med. 2019;12(11):13023–13031.
- Doi L, Williams AJ, Marryat L, Frank J. Cohort study of high maternal body mass index and the risk of adverse pregnancy and delivery outcomes in Scotland. BMJ Open. 2020;10(2):e026168. doi: 10.1136/bmjopen-2018-026168
- Mitro SD, Sanchez SE, Palomino H, Gelaye B, Williams MA. Childhood abuse, intimate partner violence, and placental abruption among Peruvian women. Ann Epidemiol. 2019;31:26–31. doi: 10.1016/j.annepidem.2018.12.003
- Ibrahimou B, Albatineh AN, Salihu HM, Gasana J. Ambient PM 2.5 aluminum and elemental carbon and placental abruption morbidity. J Occup Environ Med. 2017;59(2):148–153. doi: 10.1097/JOM.0000000000000927
- Ohira S, Motoki N, Shibazaki T, et al. Alcohol Consumption During pregnancy and Risk of placental Abnormality: The Japan environment and Children’s study. Sci Rep. 2019;9(1):10259. doi: 10.1038/s41598-019-46760-1
- Eubanks AA, Walz S, Thiel LM. Maternal risk factors and neonatal outcomes in placental abruption among patients with equal access to health care. J Matern Fetal Neonatal Med. 2021;34(13):2101–2106. doi: 10.1080/14767058.2019.1657088
- Shobeiri F, Masoumi SZ, Jenabi E. The association between maternal smoking and placenta abruption: a meta-analysis. J Matern Fetal Neonatal Med. 2017;30(16):1963–1967. doi: 10.1080/14767058.2016.1235694
- Association of Nephrologists. Clinical recommendations. Chronic kidney disease (CKD). Moscow; 2021. 233 p. (in Russ).
- Cahen-Peretz A, Sheiner E, Friger M, Walfisch A. The association between Müllerian anomalies and perinatal outcome. J Matern Fetal Neonatal Med. 2019;32(1):51–57. doi: 10.1080/14767058.2017.1370703
- Khazaei S, Jenabi E, Veisani Y. The association of Mullerian anomalies and placenta abruption: a meta-analysis. J Matern Fetal Neonatal Med. 2019;32(3):512–516. doi: 10.1080/14767058.2017.1379072
- Kitaya K, Matsubayashi H, Yamaguchi K, et al. Chronic endometritis: potential cause of infertility and obstetric and neonatal complications. Am J Reprod Immunol. 2016;75(1):13–22. doi: 10.1111/aji.12438
- Pakhomova ZhE, Komilova MS. Evaluation of Endothelial Dysfunction of the Fetoplacental Complex in Premature Abruption of Normally Positioned Placenta. The Bulletin of Contemporary Clinical Medicine. 2016;9(1):51–56. (in Russ). doi: 10.20969/vskm.2016.9(1).51-57
- Keag OE, Norman JE, Stock SJ. Long-term risks and benefits associated with cesarean delivery for mother, baby, and subsequent pregnancies: Systematic review and meta-analysis. PLoS Med. 2018;15(1):e1002494. doi: 10.1371/journal.pmed.1002494
- Kojima T, Takami M, Shindo R, et al. Perinatal outcomes of recurrent placental abruption. J Matern Fetal Neonatal Med. 2021;34(13):2192–2196. doi: 10.1080/14767058.2019.1660766
- Hiersch L, Shinar S, Melamed N, et al. Recurrent placenta-mediated complications in women with three consecutive deliveries. Obstet Gynecol. 2017;129(3):416–421. doi: 10.1097/AOG.0000000000001890
- Rudakova IS, Shifman EM, Gumenyuk EG, Tikhova GP. Preterm placental abruption. Epidemiology, risk factors. Systematic review. Gynecology, Obstetrics and Perinatology. 2021;20(3):118–133. (In Russ). doi: 10.20953/1726-1678-2021-3-118-133
Supplementary files
