Progression of antenatal preeclampsia in the postpartum period (clinical cases)
- Authors: Ignatko I.V.1, Bogomazova I.M.1, Fedyunina I.A.1, Timokhina E.V.1, Belousova V.S.1, Kuz’mina T.E.1, Kardanova M.A.1, Muravina E.L.2, Samoilova Y.A.2, Rasskazova T.V.2, Gutsu V.1
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Affiliations:
- I.M. Sechenov First Moscow State Medical University (Sechenov University)
- S.S. Yudin City Clinical Hospital
- Issue: Vol 10, No 3 (2023)
- Pages: 227-234
- Section: Clinical case reports
- URL: https://journal-vniispk.ru/2313-8726/article/view/219275
- DOI: https://doi.org/10.17816/2313-8726-2023-10-3-227-234
- ID: 219275
Cite item
Abstract
Background. Preeclampsia is recognized as one of the leading causes of maternal morbidity and mortality. In the majority of observations in the postpartum period, symptoms of preeclampsia appear in patients with antenatal hypertensive complications. These symptoms appear within the first 7–10 days after delivery and are accompanied by high blood pressure (BP) and neurologic symptoms, commonly presenting as headaches. According to the literature, common risk factors for the progression of preeclampsia in the postpartum period include maternal age over 35–40 years, obesity, cesarean section delivery, and non-Hispanic black race. Patients with progression of antenatal preeclampsia in the postpartum period often require readmission after discharge from the hospital.
Description of clinical cases. The first clinical observation involves a 25-year-old female patient was transferred to the cardiology department of the hospital on the fourth day after her first spontaneous labor due to a significant increase in BP combined with complaints of intense headache, nausea, and itching of the palms. Progression of antenatal preeclampsia complicated by the cholestasis was detected. The implementation of a complex treatment led to the normalization of clinical and laboratory parameters. In the second clinical observation, a 31-year-old first-pregnant patient at the gestational age of 27 weeks underwent emergency cesarean section due to the development of eclampsia. The patient developed thrombocytopenia and massive proteinuria a day after delivery for the first time, along with high BP, which was not present during pregnancy. The application of a personalized approach to treatment helped stabilize the maternity patient’s condition.
Conclusion. The presented clinical observations demonstrate the progression of antenatal preeclampsia in the postpartum period. In both cases, disturbances of laboratory parameters, high arterial hypertension, resistant to previously conducted antihypertensive therapy, were noted. Given that preeclampsia is a risk factor for severe complications, patients should not be discharged after delivery until clinical and laboratory parameters have completely normalized.
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##article.viewOnOriginalSite##About the authors
Irina V. Ignatko
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Email: ignatko_i_v@staff.sechenov.ru
ORCID iD: 0000-0002-9945-3848
SPIN-code: 8073-1817
Scopus Author ID: 15118951800
MD, Dr. Sci. (Med.), Professor, Corresponding Member of the Russian Academy of Sciences, Head of the Department of Obstetrics, Gynecology and Perinatology
Russian Federation, MoscowIrina M. Bogomazova
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Author for correspondence.
Email: bogomazova_i_m@staff.sechenov.ru
ORCID iD: 0000-0003-1156-7726
SPIN-code: 9414-1218
Scopus Author ID: 57191968287
MD, Cand. Sci. (Med.), Assistant Professor
Russian Federation, MoscowIrina A. Fedyunina
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Email: fedyunina_i_m@staff.sechenov.ru
ORCID iD: 0000-0002-9661-5338
SPIN-code: 1929-5879
Scopus Author ID: 57191911688
MD, Cand. Sci. (Med.), Assistant Professor
Russian Federation, MoscowElena V. Timokhina
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Email: timokhina_e_v@staff.sechenov.ru
ORCID iD: 0000-0001-6628-0023
SPIN-code: 4946-8849
Scopus Author ID: 25958373500
MD, Dr. Sci. (Med.), Assistant Professor, Professor of the Department of Obstetrics, Gynecology and Perinatology
Russian Federation, MoscowVera S. Belousova
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Email: belousova_v_s@staff.sechenov.ru
ORCID iD: 0000-0001-8332-7073
SPIN-code: 6026-9008
Scopus Author ID: 57193974992
MD, Dr. Sci. (Med.), Assistant Professor, Professor of the Department of Obstetrics, Gynecology and Perinatology
Russian Federation, MoscowTat’yana E. Kuz’mina
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Email: kuzmina_i_m@staff.sechenov.ru
ORCID iD: 0000-0001-9649-5383
SPIN-code: 7198-1382
Scopus Author ID: 57194424476
MD, Cand. Sci. (Med.), Assistant Professor
Russian Federation, MoscowMadina A. Kardanova
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Email: kardanova_i_m@staff.sechenov.ru
ORCID iD: 0000-0002-4315-0717
SPIN-code: 3895-9666
Scopus Author ID: 57194429446
MD, Cand. Sci. (Med.), Assistant Lecturer
Russian Federation, MoscowElena L. Muravina
S.S. Yudin City Clinical Hospital
Email: gkb-yudina@zdrav.mos.ru
MD, Cand. Sci. (Med.), Deputy Chief Physician for Obstetrics and Gynecology
Russian Federation, MoscowYulia A. Samoilova
S.S. Yudin City Clinical Hospital
Email: samoylova_yu_a@staff.sechenov.ru
ORCID iD: 0000-0001-7448-515X
MD, Cand. Sci. (Med.), Head of the Department of Pregnancy Pathology
Russian Federation, MoscowTat’yana V. Rasskazova
S.S. Yudin City Clinical Hospital
Email: gkb-yudina@zdrav.mos.ru
ORCID iD: 0009-0000-7681-9707
MD, Cand. Sci. (Med.), Obstetrician-Gynecologist
Russian Federation, MoscowVladimir Gutsu
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Email: gutsu_vladimir@mail.ru
ORCID iD: 0009-0000-3712-3280
Student
Russian Federation, MoscowReferences
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