Pregnancy and labor in patients with uterine fibroids

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Abstract

This review examines the etiology, pathogenesis, clinical manifestations, and impact of uterine fibroids on reproductive function. Particular attention is given to infertility, pregnancy, and labor in patients with fibroids. Uterine fibroids may be asymptomatic or present with various symptoms, including menstrual irregularities and pelvic pain. The review discusses the effect of fibroids on conception, fetal development, and the risk of pregnancy and labor complications. The influence of fibroids on pregnancy outcomes is determined by their location, size, and number. With the increasing maternal age of women planning pregnancy, the prevalence of uterine fibroids in this population is also rising. As a result, organ-preserving surgical approaches aimed at optimizing reproductive outcomes and reducing pregnancy complications have become a primary treatment strategy. However, the best management strategy that minimizes complications and alleviates symptoms remains undefined. Treatment decisions should be individualized, taking into account multiple factors and requiring thorough patient evaluation. The review underscores the importance of early detection and prevention of pregnancy-related complications in patients with uterine fibroids. Further research is essential to refine preventive measures and optimize treatment strategies for this condition.

About the authors

Yulia E. Dobrokhotova

Pirogov Russian National Research Medical University

Email: pr.dobrohotova@mail.ru
ORCID iD: 0000-0002-7830-2290
SPIN-code: 2925-9948

MD, Dr. Sci. (Medicine), Professor

Russian Federation, 1/6 Ostrovityanova st, Moscow, 117513

Aznar S. Khachatryan

Yerevan State Medical University

Email: aznardoc@yahoo.com
ORCID iD: 0009-0000-2767-8995
SPIN-code: 7707-5981

MD, Cand. Sci. (Medicine), Assistant Professor

Armenia, Yerevan

Irina Yu. Ilyina

Pirogov Russian National Research Medical University

Email: iliyina@mail.ru
ORCID iD: 0000-0001-8155-8775
SPIN-code: 5753-4380

MD, Dr. Sci. (Medicine), Professor of the Department

Russian Federation, 1/6 Ostrovityanova st, Moscow, 117513

Djamilia M. Ibragimova

Pirogov Russian National Research Medical University

Email: dgam81@mail.ru
ORCID iD: 0000-0002-8738-868X
SPIN-code: 7962-4941

MD, Cand. Sci. (Medicine), Assistant Professor

Russian Federation, 1/6 Ostrovityanova st, Moscow, 117513

Metanat R. Narimanova

Pirogov Russian National Research Medical University

Author for correspondence.
Email: safarovametanat@yandex.ru
ORCID iD: 0000-0003-0677-2952
SPIN-code: 2723-5711

MD, Cand. Sci. (Medicine), Assistant Professor

Russian Federation, 1/6 Ostrovityanova st, Moscow, 117513

Elena S. Platova

Pirogov Russian National Research Medical University

Email: lena.platova2015@yandex.ru
ORCID iD: 0009-0009-6999-4553

MD, Cand. Sci. (Medicine), Assistant Professor

Russian Federation, 1/6 Ostrovityanova st, Moscow, 117513

Olga I. Kauseva

City Clinical Hospital No. 1 named after N.I. Pirogov

Email: olga.kauseva@gmail.com
ORCID iD: 0000-0002-7117-7642
SPIN-code: 5387-8115

Ultrasound Diagnostics Doctor

Russian Federation, Moscow

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