The state of oncological care in Russia: malignant skin neoplasms (C44). Part 1. Prevalence, quality of accounting, age characteristics, localization, and histological structure (clinical-population study)

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This work represents a clinical-population study of the state of oncological care in Russia, focused on malignant skin neoplasms (C44). The study analyzes data on the prevalence of this disease, the quality of case accounting, age characteristics, and the localization and histological structure of tumors. The aim of this research is to continue the investigation into the patterns of prevalence of skin neoplasms (C44), assess the quality of primary accounting, and evaluate the impact of the coronavirus infection epidemic on analytical indicators of prevalence and patient survival. The conducted study confirmed the trend of increasing morbidity and decreasing mortality from skin neoplasms (C44) among the population of Russia and the Northwestern Federal District of the Russian Federation. A clear positive dynamics in the quality of accounting is observed. Special attention is given to the specifics of morbidity changes in neoplasms (C44) considering each age group of the population of Russia. At the population level, the age-specific mortality of patients is presented for each year of observation, analyzed in the context of five-year cohort groups. For the first time, a trend has been identified showing an increase in annual mortality from skin neoplasms (C44) after the sixth year of observation following the treatment of patients.

About the authors

Vakhtang M. Merabishvili

N. N. Petrov National Medical Research Centre of Oncology Ministry of public health of Russian Federation

Author for correspondence.
Email: MVM@niioncologii.ru

Honored Scientist of the Russian Federation, Dr.Med.Sci., Professor, Head of the Department of Cancer Statistics, N. N. Petrov National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation; Chairman of the Scientific and Medical Council for the Development of Information Systems of the Oncological Service of the Northwestern Region of Russia; Head of the Population Cancer Registry of the Northwestern Federal District of the Russian Federation

Russian Federation, Saint Petersburg

Lev V. Demidov

Blokhin National Medical Research Center of Oncology of the Russian Ministry

Email: info@ronc.ru

Dr. Med. Sci., Professor, Head of the Department of Skin Tumors of the Department of Drug Treatment, Blokhin National Medical Research Center of Oncology of the Russian Ministry

Russian Federation, Moscow

Alexey M. Belyaev

N. N. Petrov National Medical Research Centre of Oncology Ministry of public health of Russian Federation; North-Western State Medical University named after I.I. Mechnikov

Email: bam281060@yandex.ru

Dr. Med. Sci., Professor, Honored Doctor of the Russian Federation, Corresponding Member of RAS, Director of the N. N. Petrov National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation; Head of the Department of Oncology, North-Western State Medical University named after I.I. Mechnikov

Russian Federation, Saint Petersburg; Saint Petersburg

Georgy I. Gafton

N. N. Petrov National Medical Research Centre of Oncology Ministry of public health of Russian Federation

Email: center.petrova@niioncologii.ru

Dr. Med. Sci., Head of the Scientific Department of General Oncology and Urology, N. N. Petrov National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation

Russian Federation, Saint Petersburg

Igor V. Samoilenko

Blokhin National Medical Research Center of Oncology of the Russian Ministry

Email: info@ronc.ru

MD, PhD, Senior Researcher, Department of Skin Tumors, Department of Drug Treatment, Blokhin National Medical Research Center of Oncology of the Russian Ministry

Russian Federation, Moscow

Vladimir V. Perelygin

Saint Petersburg State Chemical and Pharmaceutical University of the Ministry of Health of the Russian Federation

Email: vladimir.pereligin@pharminnotech.com

Dr. Med. Sci., Professor, Honored Doctor of the Russian Federation, Head of the Industrial Ecology Department, Saint Petersburg State Chemical and Pharmaceutical University of the Ministry of Health of the Russian Federation

Russian Federation, Saint Petersburg

References

  1. Cancer Incidence in Five Continents. Volume XII. Registry Summary tables. https://ci5.iarc.fr/ci5-xii/tables/summary
  2. Cancer Incidence in Five Continents. Volume VI. IARC Scientific Publication No. 120. Edited by Parkin D. M., Muir C. S., Whelan S. L., Gao Y-T, Ferlay J, Powell J. Lyon, 1992
  3. Cancer Incidence in Five Continents. Volume VII. IARC Scientific Publication No. 143. Edited by Parkin D. M., Whelan S. L., Ferlay J, Raymond L, Young J. Lyon, 1997
  4. Cancer Incidence in Five Continents. Volume VIII. IARC Scientific Publication No. 155. Edited by Parkin D. M., Whelan S. L., Ferlay J, Teppo L, Thomas D. B. Lyon, 2002
  5. Cancer Incidence in Five Continents. Volume IX. IARC Scientific Publication No. 160. Edited by Curado M. P., Edwards B, Shin H. R., Storm H, Ferlay J, Heanue M, Boyle P. Lyon, 2007
  6. Cancer Incidence in Five Continents. Volume X. IARC Scientific Publication No. 164. Edited by Forman D., Bray F., Brewster D. H., Gombe Mbalawa C., Kohler B., Piñeros M., Steliarova-Foucher E, Swaminathan R, Ferlay J. Lyon, 2014
  7. Malignant tumors in Russia in 2015 (morbidity and mortality) / Ed. A. D. Kaprin, V. V. Starinskogo, G. V. Petrovoi. – M.: P. A. Herzen MSIOI – filial of NMRC of radiology Ministry of Public Health of the Russian Federation, 2016. – p. 250. (In Russ).
  8. Malignant tumors in Russia in 2022 (morbidity and mortality) / Ed. A. D. Kaprina, V. V. Starinskogo, A. O. Shakhzadova, I. V. Lisichnikovoi. – M.: P. A. Herzen MSIOI – filial of NMRC of radiology Ministry of Public Health of the Russian Federation, 2023. – 275 p. (In Russ).
  9. Merabishvili V. M. Coronaviruses and cancer in Russia / V. M. Merabishvili // Issues of oncology. – 2022. – Vol. 68, No. 4. – P. 381–392. – doi: 10.37469/0507-3758-2022-68-4-381-392. (In Russ).
  10. Malignant tumors in Russia in 2010 (morbidity and mortality) / Ed. V. I. Chissova, V. V. Starinskogo, G. V. Petrovoi. – M.: P. A. Herzen MSIOI, 2012. – p. 260. (In Russ).
  11. Malignant tumors in Russia in 2019 (morbidity and mortality) / Ed. A. D. Kaprina, V. V. Starinskogo, G. V. Petrovoi. – M.: P. A. Herzen MSIOI – filial of NMRC of radiology Ministry of Public Health of the Russian Federation, 2020. – p. 214. (In Russ).
  12. Malignant tumors in Russia in 2020 (morbidity and mortality) / Ed. A. D. Kaprina, V. V. Starinskogo, A. O. Shahzadovoi. – M.: P. A. Herzen MSIOI – filial of NMRC of radiology Ministry of Public Health of the Russian Federation, 2021. – p. 252. (In Russ).
  13. Malignant tumors in Russia in 2020 (morbidity and mortality) / Ed. A. D. Kaprina, V. V. Starinskogo, A. O. Shahzadovoi. – M.: P. A. Herzen MSIOI – filial of NMRC of radiology Ministry of Public Health of the Russian Federation, 2022. – p. 252. (In Russ).
  14. Malignant tumors in Russia in 2000 (morbidity and mortality) / Ed. V. I. Chissova, V. V. Starinskogo. – M.: P. A. Herzen MSIOI, 2002. – p. 264. (In Russ).
  15. Merabishvili V. M. Analytical index of accuracy // Questions of oncology. – 2018. – Vol. 64. – No. 3. – P. 445–452. (In Russ).
  16. Merabishvili V. M. Index of accuracy – the main criteria for an objective assessment of the activity of the oncological service for all localities of malignant tumors, regardless of the level of lethality of patients // Questions of Oncology. – 2019. – Vol. 65. – No. 4. – p.510–515. (In Russ).
  17. Merabishvili V. M. Oncology statistic. Part I. Second edition, expanded – Saarbrüchen, Dentschland (Germany): Lap Lambert Academic Publishing, 2015. – 223 p. (In Russ).
  18. Merabishvili V. M. Oncology statistic. Part II. Second edition, expanded – Saarbrüchen, Dentschland (Germany): Lap Lambert Academic Publishing, 2015. – 248 p. (In Russ).
  19. Garanina O. E. Non-invasive methods for diagnosing skin tumors and their potential for screening for skin melanoma: a systematic literature review / O. E. Garanina, I. V. Samoylenko, I. L. Shlivko [et al.] // Medical Council. – 2020. – No. 9. – P. 102–120. – doi: 10.21518/2079-701X-2020-9-102-120.
  20. Ligeralde-Bascones K. I., Gulmatico-Flores Z., Lim-Bueser H. G., Espinoza-Thaebtharm A., Rescober-Valencia M. C., Aguila K. P., Anupol E. B.J., Balete S. L., Barcelona M. V., Castro V. C.S., Fineza-Dela Cruz A. M.B., Lansangan P. P., Manrique A. M. B., Olitoquit K. D., Ortiz A. C.G., Palisoc E. D., Santos D. G.V., See M. R.V., Sy A. J.F., Sy G. C., Tana M. G., Tayag J. J.S., Teo H. M. T. Diagnosis and management of basal cell carcinoma: interdisciplinary consensus statements of Jose R. Reyes Memorial Medical Center, a Department of Health Tertiary Hospital in Manila, Philippines // Int J Dermatol. – 2023. – Vol. 62, No. 6. – P. 812–821.
  21. Naik P. P., Desai M. B. Basal Cell Carcinoma: A Narrative Review on Contemporary Diagnosis and Management // Oncol Ther. – 2022. – Vol. 10, No. 2. – P. 317–335.
  22. Tanese K. Diagnosis and Management of Basal Cell Carcinoma // Curr Treat Options Oncol. – 2019. – Vol. 20, No. 2. – P. 13.
  23. Lallas A., Apalla Z., Ioannides D., Argenziano G., Castagnetti F., Moscarella E., Longo C., Palmieri T., Ramundo D., Zalaudek I. Dermoscopy in the diagnosis and management of basal cell carcinoma // Future Oncol. – 2015. – Vol. 11, No. 22. – P. 2975–84.
  24. Cheng H. M., Guitera P. Systematic review of optical coherence tomography usage in the diagnosis and management of basal cell carcinoma // Br J Dermatol. – 2015. – Vol. 173, No. 6. – P. 1371–80.
  25. Fabiano A., Argenziano G., Longo C., Moscarella E., Specchio F., Lallas A. Dermoscopy as an adjuvant tool for the diagnosis and management of basal cell carcinoma // G Ital Dermatol Venereol. – 2016. – Vol. 151, No. 5. – P. 530–4.
  26. Reiter O., Mimouni I., Gdalevich M., Marghoob A. A., Levi A., Hodak E., Leshem Y. A. The diagnostic accuracy of dermoscopy for basal cell carcinoma: A systematic review and meta-analysis // J Am Acad Dermatol. – 2019. – Vol. 80, No. 5. – P. 1380–1388.
  27. Klein C. M., Sivesind T. E., Dellavalle R. P. From the Cochrane Library: Visual Inspection and Dermoscopy, Alone or in Combination, for Diagnosing Keratinocyte Skin Cancers in Adults // JMIR Dermatol. – 2024. – Vol. 7. – P. e41657.
  28. Dinnes J., Deeks J. J., Chuchu N., Matin R. N., Wong K. Y., Aldridge R. B., Durack A., Gulati A., Chan S. A., Johnston L., Bayliss S. E., Leonardi-Bee J., Takwoingi Y., Davenport C., O’Sullivan C., Tehrani H., Williams H. C., Cochrane Skin Cancer Diagnostic Test Accuracy G. Visual inspection and dermoscopy, alone or in combination, for diagnosing keratinocyte skin cancers in adults // Cochrane Database Syst Rev. – 2018. – Vol. 12, No. 12. – P. CD011901.
  29. Lallas A., Tzellos T., Kyrgidis A., Apalla Z., Zalaudek I., Karatolias A., Ferrara G., Piana S., Longo C., Moscarella E., Stratigos A., Argenziano G. Accuracy of dermoscopic criteria for discriminating superficial from other subtypes of basal cell carcinoma // J Am Acad Dermatol. – 2014. – Vol. 70, No. 2. – P. 303–11.
  30. Lallas A., Pyne J., Kyrgidis A., Andreani S., Argenziano G., Cavaller A., Giacomel J., Longo C., Malvestiti A., Moscarella E., Piana S., Specchio F., Hofmann-Wellenhof R., Zalaudek I. The clinical and dermoscopic features of invasive cutaneous squamous cell carcinoma depend on the histopathological grade of differentiation // Br J Dermatol. – 2015. – Vol. 172, No. 5. – P. 1308–15.
  31. Hernandez C., del Boz J., de Troya M. Can high-frequency skin ultrasound be used for the diagnosis and management of Basal cell carcinoma? // Actas Dermosifiliogr. – 2014. – Vol. 105, No. 2. – P. 107–11.
  32. Ferrante di Ruffano L., Dinnes J., Chuchu N., Bayliss S. E., Takwoingi Y., Davenport C., Matin R. N., O’Sullivan C., Roskell D., Deeks J. J., Williams H. C., Cochrane Skin Cancer Diagnostic Test Accuracy G. Exfoliative cytology for diagnosing basal cell carcinoma and other skin cancers in adults // Cochrane Database Syst Rev. – 2018. – Vol. 12, No. 12. – P. CD013187.

Supplementary files

Supplementary Files
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1. JATS XML
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2. Fig. 1. Cancer incidence in Five Continents. Skin (except melanoma). C44. Males. Vol. XII IARC. 2013–2017 [1, 7, 8]

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3. Fig. 2. Cancer incidence in Five Continents. Skin (except melanoma). C44. Females. Vol. XII IARC. 2013–2017 [1, 7, 8]

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4. Fig. 3. Age-related rates of the incidence of skin cancer (C44) in the male population in some countries. IARC “Cancer Incidence in Five Continents”, vol. XII. [1, 7, 8]

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5. Fig. 4. Age-related rates of the incidence of skin cancer (C44) in the female population in some countries. IARC “Cancer Incidence in Five Continents”, vol. XII. [1, 7, 8]

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6. Fig. 5. Dynamic of skin cancer (C44) morbidity in Russia and NWFD of RF. M+F. ASR (W) [7, 8, 10–13]

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7. Fig. 6 + table. Age-related dynamics of skin cancer (C44) incidence in Russia. M+F. 2000, 2022. [8, 14]

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8. Fig. 7 + table. Age-related dynamics of skin cancer (C44) incidence in Russia. Males. 2000, 2022. [8, 14]

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9. Fig. 8 + table. Age-related dynamics of skin cancer (C44) incidence in Russia. Females. 2000, 2022. [8, 14]

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10. Fig. 9 + table. Dynamics of annual mortality of patients with skin cancer (C44) in the NWFD in four cohort groups. DB PCR of the NWFD

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