Peculiarities of the heart rate variability at patients with acute disorder of cerebral circulation depending on localisation of ischemic damage
- Authors: Nikolaev V.I.1, Denisenko N.P.1, Brega A.V.1, Denisenko M.D.1
-
Affiliations:
- North-Western State Medical University named after I.I. Mechnikov
- Issue: Vol 10, No 3 (2019)
- Pages: 63-69
- Section: Original studies
- URL: https://journal-vniispk.ru/pediatr/article/view/15683
- DOI: https://doi.org/10.17816/PED10363-69
- ID: 15683
Cite item
Full Text
Abstract
Features of the heart rate variability at patients with acute disorder of cerebral circulation depending on localisation of ischemic damage and type of hemodynamics were studied in acute period of disease and in a condition of relative functional rest. Surveyed men and women (30–55 years old) were divided into 3 groups: patients with ischemic damage to the area of the left average brain artery, right average brain artery and with ischemia in vertebro-basilar department. According to indicators of the integral rheography of the body which was carried out in the acute period of a disease, patients of each group were divided into subgroups depending on hemodynamics type – with hyper dynamic, hypo dynamic and normo dynamic type of blood circulation. It was revealed that the highest activity of sympathetic link of regulation and also higher values of the index of tension and the index of vegetative balance characterized patients with ischemia in the area of right average brain artery and hyper dynamic type of blood circulation. The indicator of activity of regulatory systems characterized “overstrain of regulatory mechanisms” and also “exhaustion of mechanisms of regulation” at patients of this group in the acute period. However upon repeated examination 7 days later revealed the significant reduction of the values of the indicator of activity of regulatory systems. Similar indicators of the heart rate variability were found at patients with ischemic damage in the area of right average brain artery and normo dynamic type of blood circulation. Thus, it was detected that the greatest disorders of regulation of the cardiovascular system were characteristic of patients with ischemia in the area of right average brain artery both hyper dynamic and normo dynamic blood circulation types. Activation of parasympathetic and suppression of sympathetic link of regulation were noted in all patients on the seventh day of hospital stay regardless of localisation of ischemic damage and type of hemodynamics.
Full Text
##article.viewOnOriginalSite##About the authors
Valentin I. Nikolaev
North-Western State Medical University named after I.I. Mechnikov
Author for correspondence.
Email: valentin.nikolaev@szgmu.ru
MD, PhD, Dr Med Sci, Professor, Head, Department of Pathological Physiology
Russian Federation, Saint PetersburgNataliya P. Denisenko
North-Western State Medical University named after I.I. Mechnikov
Email: nataliya_denisen@mail.ru
MD, PhD, Dr Med Sci, Professor, Department of Pathological Physiology
Russian Federation, Saint PetersburgAnastasiya V. Brega
North-Western State Medical University named after I.I. Mechnikov
Email: sonata-lyna@mail.ru
MD, PhD, Assistant Professor, Department of Pathological Physiology
Russian Federation, Saint PetersburgMarya D. Denisenko
North-Western State Medical University named after I.I. Mechnikov
Email: maryadenisenko@yandex.ru
MD, PhD, Associate Professor, Department of Pathological Physiology
Russian Federation, Saint PetersburgReferences
- Захарушкина И.В. Церебральные инсульты у мужчин и женщин молодого возраста: Автореф. дис. … д-ра мед. наук. – Иваново, 2004. – 39 с. [Zakharushkina IV. Tserebral’nye insul’ty u muzhchin i zhenshchin molodogo vozrasta. [dissertation] Ivanovo; 2004. 39 р. (In Russ.)]. Доступно по: https://search.rsl.ru/ru/record/01002664582. Дата обращения: 14. 03. 2019.
- Кадыков, А.С., Шахпаронова Н.В. Особенности нарушения мозгового кровообращения (инсультов) в молодом возрасте // Новые медицинские технологии. – 2010. – № 4. – С. 11–16. [Kadykov AS, Shakhparonova NV. Features of cerebral circulation (stroke) disorders in young-aged patients. Vestnik nevrologii, psikhiatrii i neirokhirurgii. 2010;(4):23-28. (In Russ.)]
- Кириченко А.А. Депрессия, беспокойство и сердечно-сосудистая система // Лечащий врач. – 2002. – № 12 — С. 58–61. [Kirichenko AA. depressiya, bespokojstvo i serdechno-sosudistaya sistema. Practitioner. 2002;(12):58-61. (In Russ.)]
- Котов С.В., Исакова Е.В. Клинико-экономические показатели инсульта в Московской области // Журнал неврологии и психиатрии им. С.С. Корсакова. Инсульт (приложение к журналу). Спецвыпуск. – 2007. – С. 207. [Kotov SV, Isakova EV. Kliniko-ekonomicheskie pokazateli insul’ta v Moskovskoj oblasti. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. Insul’t (prilozhenie k zhurnalu). 2007. Spetsvypusk. Р. 207. (In Russ.)]
- Николаев В.И., Денисенко М.Д. Особенности формирования эмоционального напряжения и изменения гемодинамики у человека во время психоэмоционального стресса // Профилактическая и клиническая медицина. – 2010. – № 1. – С. 47–50. [Nikolaev VI, Denisenko MD. Special characteristics of emotional tension and hemodynamic change in man during psychoemotional stress. Preventive and clinicalmedicine. 2010;(1):47-50. (In Russ.)]
- Николаев В.И., Денисенко Н.П., Денисенко М.Д., и др. Особенности адаптивных реакций у людей с разным типом гемодинамики // Таврический медико-биологический вестник. – 2012. – Т. 15. – № 3–2. – С. 183–186. [Nikolaev VI, Denisenko NP, Denisenko MD, et al. Osobennosti adaptivnykh reaktsij u lyudej s raznym tipom gemodinamiki Tavricheskij mediko-biologicheskij vestnik. 2012;15(3–2):183-186. (In Russ.)]
- Пуршев В.Ю. Цереброваскулярная патология с позиции психосоматической медицины // Медицинский альманах. – 2009. – № 4. – С. 182–185. [Purshev VY. Cerebrovascular pathology from the position of psychosomatic medicine. Meditsinskij al’manakh. 2009;(4):182-185. (In Russ.)]
- Суслина З.А., Варакин Ю.Я., Верещагин Н.В. Сосудистые заболевания головного мозга: эпидемиология, патогенетические механизмы, профилактика. – 3-е изд. – М.: МЕДпресс-информ, 2009. – 350 с. [Suslina ZA, Varakin YuYa, Vereshchagin NV. Sosudistye zabolevaniya golovnogo mozga: epidemiologiya, patogeneticheskie mekhanizmy, profilaktika. 3rd ed. Moscow: MEDpress-inform; 2009. 350 р. (In Russ.)]
Supplementary files
