Whole-cell bacterial biosensors for the detection of aromatic hydrocarbons and their chlorinated derivatives (Review)


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Аннотация

The review summarizes the data on new directions in biosensor technologies based on whole bacterial cells. Biosensors for the monitoring of mono(poly)aromatic hydrocarbons and their chlorinated derivatives, which are constructed with genetically modified bacterial cells bearing a reporter gene fusion, are considered. The operating principle of these biosensors is based on the expression of reporter genes (luc, lux, gfp, rfp) under the control of a promoter and a regulator that specifically respond to a detected compound.

Авторлар туралы

E. Plotnikova

Perm State National Research University; Institute of Ecology and Genetics of Microorganisms

Хат алмасуға жауапты Автор.
Email: peg_el@mail.ru
Ресей, Perm, 614990; Perm, 614081

E. Shumkova

Perm State National Research University; Bach Institute of Biochemistry, Fundamental Principles of Biotechnology, Federal Research Center

Email: peg_el@mail.ru
Ресей, Perm, 614990; Moscow, 119071

M. Shumkov

Bach Institute of Biochemistry, Fundamental Principles of Biotechnology, Federal Research Center

Email: peg_el@mail.ru
Ресей, Moscow, 119071

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© Pleiades Publishing, Inc., 2016