THREE-LOCUS TLR10–TLR1–TLR6 HAPLOTYPES DISTRIBUTION IN TATARS OF THE CHELYABINSK REGION IN COMPARISON WITH THE POPULATIONS OF EURASIA
- Authors: Evdokimov A.V.1
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Affiliations:
- Federal State Budgetary Educational Institution of Higher Education “Chelyabinsk State University”
- Issue: Vol 22, No 2-2 (2019)
- Pages: 763-765
- Section: ORIGINAL ARTICLES
- URL: https://journal-vniispk.ru/1028-7221/article/view/119513
- DOI: https://doi.org/10.31857/S102872210006706-1
- ID: 119513
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Abstract
This article describes the cluster TLR10-TLR1-TLR6 haplotypes distribution features observed in Tatars of the Chelyabinsk Region. For the fi rst time in Tatars population the frequencies of three-locus haplotypes – 721A>C in TLR10 gene, 1805T>G in TLR1 gene and 745C>T in TLR6 gene – were obtained. The most similar haplotype frequencies among the world Eurasian populations were identified in Toscans and Iberians, while other Eurasian populations differed significantly from Tatars. The data obtained may be useful in the study of predictors of auto-inflammatory and infectious diseases.
About the authors
A. V. Evdokimov
Federal State Budgetary Educational Institution of Higher Education “Chelyabinsk State University”
Author for correspondence.
Email: avdax@yandex.ru
candidate of biological sciences, assistant professor at the Department of microbiology, immunology and general biology of the biology faculty,
Chelyabinsk
Russian FederationReferences
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